Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3914454 | 1.00 | ADRB2 (0.40) | ADRB2MEN1ALDH1A1KMT2ATRPA1 | |
| SCHEMBL7054852 | 0.78 | ALDH1A1 (0.47) | ADRB2MEN1ALDH1A1KMT2ATAAR1 | |
| SCHEMBL27598444 | 0.78 | HPGD (0.42) | MEN1ALDH1A1KMT2ATRPA1TAAR1 | |
| SCHEMBL10755711 | 0.77 | MAOB (0.46) | MEN1KMT2ATRPA1 | |
| SCHEMBL7453483 | 0.74 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL5219600 | 0.73 | ANPEP (0.46) | MEN1ALDH1A1KMT2A | |
| SCHEMBL3915043 | 0.73 | MEN1 (0.59) | ADRB2MEN1ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL3914456 | 0.73 | MEN1 (0.59) | ADRB2MEN1ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL5391447 | 0.73 | ABCB1 (0.46) | ADRB2MEN1KMT2ASIGMAR1 | |
| SCHEMBL1005591 | 0.72 | SIGMAR1 (0.68) | MEN1ALDH1A1KMT2ATRPA1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498436-B2 | Substituted hydroxyethylamines | PHARMACIA & UPJOHN COMPANY LLC (US) | 2009-03-03 | — | — | US | disclosed |
| US-20060106256-A1 | Substituted hydroxyethylamines | PHARMACIA & UPJOHN COMPANY | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106256-A1 | Substituted hydroxyethylamines | HNMT, PNMT, BCHE | ADRB2 710/4885MEN1 815/4885ALDH1A1 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.