Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27598444 | 0.90 | HPGD (0.42) | ALDH1A1CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL5219600 | 0.83 | ANPEP (0.46) | ALDH1A1CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL5391447 | 0.82 | ABCB1 (0.46) | CYP1A2CYP2D6MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4044904 | 0.78 | EPHX1 (0.51) | KDM4EL3MBTL1 | |
| SCHEMBL3914454 | 0.78 | ADRB2 (0.40) | ALDH1A1MEN1KMT2AADRB2TAAR1 | |
| SCHEMBL3915041 | 0.78 | ADRB2 (0.40) | ALDH1A1MEN1KMT2AADRB2TAAR1 | |
| SCHEMBL3468847 | 0.77 | MEN1 (0.34) | ALDH1A1CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL7051118 | 0.76 | OPRD1 (0.47) | ALDH1A1CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL27592798 | 0.76 | KDM4E (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A | |
| Methylamine SCHEMBL28758829 | 0.75 | SIGMAR1 (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |