Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 3/20 | 1.00 |
| ▸ | PTPN7 | P35236 | 2/20 | 1.00 |
| ▸ | PTPRC | P08575 | 1/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.76 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.76 |
| ▸ | PTPRJ | Q12913 | 1/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31186847 | 1.00 | PTPN11 (1.00) | PTPN11PTPN7PTPRCALOX15PTPN1 | |
| SCHEMBL2401970 | 1.00 | PTPN11 (1.00) | PTPN11PTPN7PTPRCALOX15PTPN1 | |
| SCHEMBL14154415 | 0.86 | PTPN11 (1.00) | PTPN11PTPN7PTPRCALOX15PTPN1 | |
| SCHEMBL13738903 | 0.86 | PTPN11 (1.00) | PTPN11PTPN7PTPRCALOX15PTPN1 | |
| SCHEMBL2401972 | 0.86 | PTPN11 (1.00) | PTPN11PTPN7PTPRCALOX15PTPN1 | |
| SCHEMBL29391398 | 0.86 | PTPN11 (1.00) | PTPN11PTPN7PTPRCALOX15PTPN1 | |
| SCHEMBL30542884 | 0.86 | PTPN11 (1.00) | PTPN11PTPN7PTPRCALOX15PTPN1 | |
| SCHEMBL13738901 | 0.86 | PTPN11 (1.00) | PTPN11PTPN7PTPRCALOX15PTPN1 | |
| SCHEMBL2401966 | 0.85 | PTPN11 (0.98) | PTPN11PTPN7PTPRCALOX15PTPN1 | |
| SCHEMBL29624127 | 0.83 | PTPN11 (0.71) | PTPN11PTPN7PTPRCALOX15PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8100020-B2 | Compliant and wireless health monitoring sensors for composite structures | Lumimove, Inc., a Missouri Corporation (US) | 2012-01-24 | — | — | US | claimed |
| JP-2011525240-A | — | — | 2011-09-15 | — | — | JP | claimed |
| EP-2297559-A2 | COMPLIANT AND WIRELESS HEALTH MONITORING SENSORS FOR COMPOSITE STRUCTURES | Lumimove, Inc., Dba Crosslink (US) | 2011-03-23 | — | — | EP | claimed |
| US-20100095781-A1 | COMPLIANT AND WIRELESS HEALTH MONITORING SENSORS FOR COMPOSITE STRUCTURES | LUMIMOVE, INC., D/B/A CROSSLINK (US) | 2010-04-22 | — | — | US | claimed |
| WO-2009155367-A2 | COMPLIANT AND WIRELESS HEALTH MONITORING SENSORS FOR COMPOSITE STRUCTURES | LUMIMOVE, INC., D/B/A CROSSLINK (US) | 2009-12-23 | — | — | WO | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| CN-117838863-B | Nucleic acid molecule for inhibiting D2HGDH, inhibitor and application thereof | 厦门大学 | 2025-03-11 | — | — | CN | disclosed |
| WO-2024092274-A2 | ENDOCYTIC AGENTS | BIOVENTURES, LLC (US) | 2024-05-02 | — | — | WO | disclosed |
| CN-117838863-A | Nucleic acid molecule for inhibiting D2HGDH, inhibitor and application thereof | 厦门大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-116212048-A | Cell surface coupling of nanoparticles | 麻省理工学院 | 2023-06-06 | — | — | CN | disclosed |
| US-20220185860-A1 | CELL SURFACE COUPLING OF NANOPARTICLES | IRVINE, DARRELL | 2022-06-16 | — | — | US | disclosed |
| US-20220151921-A1 | MONOCYTE-SELECTIVE DRUG DELIVERY SYSTEM USING SINGLE-WALLED CARBON NANOTUBES TO INDUCE EFFEROCYTOSIS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2022-05-19 | — | — | US | disclosed |
| US-11261226-B2 | Cell surface coupling of nanoparticles | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (MITN1) (US) | 2022-03-01 | — | — | US | disclosed |
| US-5160457-A | Dopes, fibers, films, moldings, sheets | ALLIED-SIGNAL INC. (US) | 1992-11-03 | — | — | US | disclosed |
| WO-1992018572-A2 | METHOD OF PROCESSING NEUTRAL POLYANILINES IN SOLVENT AND SOLVENT MIXTURES | ALLIED-SIGNAL INC. (US) | 1992-10-29 | — | — | WO | disclosed |
| WO-1992015632-A1 | THERMALLY INDUCED CHAIN COUPLING IN SOLID STATE POLYANILINE | ALLIED-SIGNAL INC. (US) | 1992-09-17 | — | — | WO | disclosed |
| WO-1992011644-A1 | METHOD OF PROCESSING ELECTRICALLY CONDUCTIVE POLYANILINES IN SOLVENT MIXTURES | ALLIED-SIGNAL INC. (US) | 1992-07-09 | — | — | WO | disclosed |
| WO-1992011645-A1 | METHOD FOR PROCESSING ELECTRICALLY CONDUCTIVE POLYANILINES IN LEWIS-BASE SOLVENTS | ALLIED-SIGNAL INC. (US) | 1992-07-09 | — | — | WO | disclosed |
| EP-0461182-A1 | THERMALLY STABLE FORMS OF ELECTRICALLY CONDUCTIVE POLYANILINE. | ALLIED SIGNAL INC (US) | 1991-12-18 | — | — | EP | disclosed |
| WO-1990010297-A1 | THERMALLY STABLE FORMS OF ELECTRICALLY CONDUCTIVE POLYANILINE | ALLIED-SIGNAL INC. (US) | 1990-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185860-A1 | CELL SURFACE COUPLING OF NANOPARTICLES | EPCAM, CD47, CD63 | THRB 1171/4885PTPN11 142/4885PTPN7 131/4885 |
| US-11261226-B2 | Cell surface coupling of nanoparticles | EPCAM, CD47, CD63 | THRB 1171/4885PTPN11 142/4885PTPN7 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.