Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520840 | 0.86 | TSHR (0.49) | TSHRALDH1A1TDP1HSD17B10CYP3A4 | |
| SCHEMBL11755785 | 0.83 | TSHR (0.49) | TSHRALDH1A1TDP1HSD17B10CYP3A4 | |
| SCHEMBL11802146 | 0.83 | TSHR (0.49) | TSHRALDH1A1TDP1HSD17B10CYP3A4 | |
| Hydrochloric Acid SCHEMBL11755802 | 0.81 | TSHR (0.47) | TSHRALDH1A1TDP1HSD17B10CYP3A4 | |
| SCHEMBL10515858 | 0.81 | MCL1 (0.42) | TSHRALDH1A1TDP1CYP3A4LMNA | |
| SCHEMBL28391840 | 0.79 | TSHR (0.41) | TSHRALDH1A1TDP1HSD17B10CYP3A4 | |
| Potassium Ion SCHEMBL10515759 | 0.78 | MCL1 (0.42) | TSHRALDH1A1TDP1CYP3A4LMNA | |
| SCHEMBL9568264 | 0.77 | TSHR (0.56) | TSHRALDH1A1TDP1HSD17B10LMNA | |
| SCHEMBL58062 | 0.75 | TSHR (0.67) | TSHRALDH1A1TDP1HSD17B10CYP3A4 | |
| SCHEMBL28668057 | 0.75 | TSHR (0.67) | TSHRALDH1A1TDP1HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110964652-B | Dinitro sodium toluene sulfonate degrading bacteria and screening method and application thereof | 中国科学院青岛生物能源与过程研究所 | 2022-04-22 | — | — | CN | claimed |
| CN-110964652-A | Dinitro sodium toluene sulfonate degrading bacteria and screening method and application thereof | 中国科学院青岛生物能源与过程研究所 | 2020-04-07 | — | — | CN | claimed |
| US-8192511-B2 | Methods and compositions for decreasing carbon emissions | WEI PICHANG (CN) | 2012-06-05 | — | — | US | claimed |
| US-20090320728-A1 | METHODS AND COMPOSITIONS FOR DECREASING CARBON EMISSIONS | WEI PICHANG | 2009-12-31 | — | — | US | claimed |
| CN-118980097-A | Alkaline wastewater incinerator and environment-friendly treatment control method thereof | 湖北东方化工有限公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-110964652-B | Dinitro sodium toluene sulfonate degrading bacteria and screening method and application thereof | 中国科学院青岛生物能源与过程研究所 | 2022-04-22 | — | — | CN | disclosed |
| CN-113354007-A | Process and device for treating alkaline wastewater in polynitrotoluene production | 湖北东方化工有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-110964652-A | Dinitro sodium toluene sulfonate degrading bacteria and screening method and application thereof | 中国科学院青岛生物能源与过程研究所 | 2020-04-07 | — | — | CN | disclosed |
| US-8192511-B2 | Methods and compositions for decreasing carbon emissions | WEI PICHANG (CN) | 2012-06-05 | — | — | US | disclosed |
| US-20090320728-A1 | METHODS AND COMPOSITIONS FOR DECREASING CARBON EMISSIONS | WEI PICHANG | 2009-12-31 | — | — | US | disclosed |