Acrolein

Acrolein

SCHEMBL3930769

C=C.C=CC=O.CCOC(C)OCC

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
TRPA1 O75762 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrolein SCHEMBL157907 0.98 LMNA (0.60) LMNATRPA1ALDH1A1TSHRTHRB
Acrolein SCHEMBL35989 0.93 LMNA (0.55) LMNATRPA1ALDH1A1TSHRTHRB
Acrolein SCHEMBL8404934 0.89 LMNA (0.50) LMNATRPA1ALDH1A1TSHR
Butanedione SCHEMBL8338208 0.87 LMNA (0.48) LMNATRPA1ALDH1A1TSHR
1,3-Propanediol SCHEMBL8401501 0.86 LMNA (0.46) LMNATRPA1ALDH1A1TSHR
Propylene Glycol SCHEMBL9721324 0.86 LMNA (0.46) LMNATRPA1ALDH1A1TSHR
Acetaldehyde SCHEMBL22361219 0.85 LMNA (0.63) LMNATSHRTHRB
Butadiene SCHEMBL625826 0.85 LMNA (0.71) LMNATHRB
SCHEMBL4293299 0.85 LMNA (0.71) LMNAALDH1A1THRB
SCHEMBL20536819 0.85 LMNA (0.50) LMNATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1638912-A2 PROCESS FOR THE PREPARATION OF CINNAMALDEHYDE COMPOUNDS Lymphosign Inc. (CA) 2006-03-29 EP claimed
US-20050033090-A1 Process for the preparation of cinnamaldehyde compounds LYMPHOSIGN INC. (CA) 2005-02-10 US claimed
WO-2005000777-A2 PROCESS FOR THE PREPARATION OF CINNAMALDEHYDE COMPOUNDS LYMPHOSIGN INC. (CA) 2005-01-06 WO claimed
EP-1035179-A1 Ink-jet printing ink compositions having superior smear-fastness Hewlett-Packard Company (US) 2000-09-13 EP claimed
US-20250320402-A1 SYSTEMS AND METHODS FOR SCAVENGING SULFUR-CONTAINING MATERIALS USING A PRECURSOR SCAVENGER MATERIAL CAMERON INTERNATIONAL CORPORATION 2025-10-16 US disclosed
EP-3510010-B1 TASTE MODULATING ALDEHYDE TAKASAGO PERFUMERY CO LTD (JP) 2023-09-06 EP disclosed
US-11540542-B2 Taste modulating aldehydes TAKASAGO INTERNATIONAL CORPORATION (JP) 2023-01-03 US disclosed
EP-3510010-A1 TASTE MODULATING ALDEHYDES Takasago International Corporation (JP) 2019-07-17 EP disclosed
US-20190208806-A1 TASTE MODULATING ALDEHYDES TAKASAGO INTERNATIONAL CORPORATION (JP) 2019-07-11 US disclosed
WO-2018049352-A1 TASTE MODULATING ALDEHYDES TAKASAGO INTERNATIONAL CORPORATION (USA) (US) 2018-03-15 WO disclosed
US-7537879-B2 Chemically amplified, sensitive to wavelengths (300 nm - 100 nm); comprises a novel polymer with a sulfone group pendant from a polymer backbone that is insoluble in an aqueous alkaline solution and has acidic moiety protected with acid labile group, and a compound that producing an acid upon irradiation AZ ELECTRONIC MATERIALS USA CORP. (US) 2009-05-26 US disclosed
EP-1828843-A1 PHOTORESIST COMPOSITION FOR DEEP UV AND PROCESS THEREOF AZ Electronic Materials USA Corp. (US) 2007-09-05 EP disclosed
US-20060110677-A1 Photoresist composition for deep UV and process thereof MERCK PATENT GMBH (DE) 2006-05-25 US disclosed
EP-1638912-A2 PROCESS FOR THE PREPARATION OF CINNAMALDEHYDE COMPOUNDS Lymphosign Inc. (CA) 2006-03-29 EP disclosed
EP-1035179-B1 Ink-jet printing ink compositions having superior smear-fastness HEWLETT PACKARD CO (US) 2006-02-22 EP disclosed
WO-2005059652-A2 PHOTORESIST COMPOSITION FOR DEEP UV AND PROCESS THEREOF AZ ELECTRONIC MATERIALS USA CORP. (DE) 2005-06-30 WO disclosed
US-20050130058-A1 Photoresist composition for deep UV and process thereof MERCK PATENT GMBH (DE) 2005-06-16 US disclosed
US-20050033090-A1 Process for the preparation of cinnamaldehyde compounds LYMPHOSIGN INC. (CA) 2005-02-10 US disclosed
WO-2005000777-A2 PROCESS FOR THE PREPARATION OF CINNAMALDEHYDE COMPOUNDS LYMPHOSIGN INC. (CA) 2005-01-06 WO disclosed
EP-1035179-A1 Ink-jet printing ink compositions having superior smear-fastness Hewlett-Packard Company (US) 2000-09-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050033090-A1 Process for the preparation of cinnamaldehyde compounds CES2, MCCC2, BCKDK LMNA 106/4885TRPA1 2484/4885ALDH1A1 70/4885
US-11540542-B2 Taste modulating aldehydes TAS2R10, TAS2R50, TAS2R1 LMNA 4718/4885TRPA1 31/4885ALDH1A1 39/4885
US-20190208806-A1 TASTE MODULATING ALDEHYDES TAS2R10, TAS2R50, TAS2R1 LMNA 4718/4885TRPA1 31/4885ALDH1A1 39/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.