Demannose

Demannose

SCHEMBL20701790

CCOC(N)=O.O=CC(O)C(O)C(O)C(O)CO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.48
USP2 O75604 1/20 0.37
SLCO1B1 Q9Y6L6 1/20 0.37
LMNA P02545 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PDE4A P27815 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demannose SCHEMBL20701787 1.00 ALOX15 (0.48) ALOX15USP2SLCO1B1LMNAL3MBTL1
Demannose SCHEMBL5541835 0.85 LMNA (0.47) USP2SLCO1B1LMNAL3MBTL1PDE4A
Demannose SCHEMBL11509807 0.85 LMNA (0.47) USP2SLCO1B1LMNAL3MBTL1PDE4A
Demannose SCHEMBL3935915 0.84 LMNA (0.35) USP2SLCO1B1LMNAL3MBTL1PDE4A
Demannose SCHEMBL18209341 0.83 LMNA (0.44) ALOX15USP2SLCO1B1LMNAL3MBTL1
Demannose SCHEMBL27656917 0.83 LMNA (0.44) ALOX15USP2SLCO1B1LMNAL3MBTL1
Demannose SCHEMBL15066411 0.83 GLO1 (0.40) USP2SLCO1B1LMNAL3MBTL1PDE4A
Demannose SCHEMBL25270061 0.82 LMNA (0.48) USP2SLCO1B1LMNAL3MBTL1PDE4A
Demannose SCHEMBL7268551 0.82 LMNA (0.48) USP2SLCO1B1LMNAL3MBTL1PDE4A
Demannose SCHEMBL15085556 0.81 TSHR (0.39) USP2SLCO1B1LMNAL3MBTL1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117603426-A Post-crosslinking amphiphilic polyurethane, preparation method thereof and application thereof in glucose sensor 江苏鱼跃凯立特生物科技有限公司 2024-02-27 CN claimed
US-20240158476-A1 MESOPOROUS NITRIC OXIDE-RELEASING SILICA PARTICLES, METHODS OF MAKING, AND USES THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2024-05-16 US disclosed
CN-117603426-A Post-crosslinking amphiphilic polyurethane, preparation method thereof and application thereof in glucose sensor 江苏鱼跃凯立特生物科技有限公司 2024-02-27 CN disclosed
CN-117603426-A Post-crosslinking amphiphilic polyurethane, preparation method thereof and application thereof in glucose sensor 江苏鱼跃凯立特生物科技有限公司 2024-02-27 CN disclosed
US-11897775-B2 Mesoporous nitric oxide-releasing silica particles, methods of making, and uses thereof UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-02-13 US disclosed
US-20210380420-A1 MESOPOROUS NITRIC OXIDE-RELEASING SILICA PARTICLES, METHODS OF MAKING, AND USES THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2021-12-09 US disclosed
US-11117808-B2 Mesoporous nitric oxide-releasing silica particles, methods of making, and uses thereof UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2021-09-14 US disclosed
US-20190039910-A1 MESOPOROUS NITRIC OXIDE-RELEASING SILICA PARTICLES, METHODS OF MAKING, AND USES THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2019-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240158476-A1 MESOPOROUS NITRIC OXIDE-RELEASING SILICA PARTICLES, METHODS OF MAKING, AND USES THEREOF NOS1, NOS2, DDO ALOX15 259/4885USP2 998/4885SLCO1B1 834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.