SCHEMBL3937705

SCHEMBL3937705

O=C(Nc1cccnc1)c1cc([N+](=O)[O-])ccc1Cl

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.82
CYP3A4 P08684 2/20 0.73
MAPK1 P28482 2/20 0.73
PPARG P37231 2/20 0.73
ALOX15 P16050 1/20 0.73
PPARA Q07869 1/20 0.73
MEN1 O00255 4/20 0.73
KMT2A Q03164 4/20 0.73
RORC P51449 4/20 0.73
MAPT P10636 2/20 0.73
LMNA P02545 1/20 0.73
TP53 P04637 1/20 0.73
CYP1A2 P05177 1/20 0.73
CYP2D6 P10635 1/20 0.73
CYP2C9 P11712 1/20 0.73
PKM P14618 1/20 0.73
TSHR P16473 1/20 0.73
NFKB1 P19838 1/20 0.73
CYP2C19 P33261 1/20 0.73
THPO P40225 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7128348 0.93 SMN1; SMN2 (0.72) SMN1; SMN2CYP3A4MAPK1PPARGALOX15
SCHEMBL7119714 0.92 SMN1; SMN2 (0.71) SMN1; SMN2CYP3A4MAPK1PPARGALOX15
SCHEMBL7122946 0.90 SMN1; SMN2 (0.67) SMN1; SMN2CYP3A4MAPK1PPARGALOX15
SCHEMBL7123399 0.89 SMN1; SMN2 (0.71) SMN1; SMN2CYP3A4MAPK1PPARGALOX15
SCHEMBL26758011 0.88 SMN1; SMN2 (0.74) SMN1; SMN2CYP3A4MAPK1PPARGALOX15
SCHEMBL7129863 0.86 SMN1; SMN2 (0.67) SMN1; SMN2CYP3A4MAPK1PPARGALOX15
SCHEMBL3936626 0.85 SMN1; SMN2 (0.71) SMN1; SMN2CYP3A4MAPK1PPARGALOX15
SCHEMBL3933183 0.85 SMN1; SMN2 (0.71) SMN1; SMN2CYP3A4MEN1KMT2AMAPT
SCHEMBL2128178 0.85 SMN1; SMN2 (1.00) SMN1; SMN2CYP3A4MAPK1PPARGALOX15
SCHEMBL29369085 0.85 SMN1; SMN2 (1.00) SMN1; SMN2CYP3A4MAPK1PPARGALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030130343-A1 Fat accumulation-modulating compounds ADIPOGENIX, INC. (US) 2003-07-10 US claimed
WO-2003013516-A1 FAT ACCUMULATION-MODULATING COMPOUNDS ADIPOGENIX, INC. (US) 2003-02-20 WO claimed
EP-4666856-A2 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Corteva Agriscience LLC (US) 2025-12-24 EP disclosed
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2025-12-09 US disclosed
US-20250359552-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-27 US disclosed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP disclosed
US-20250134105-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-01 US disclosed
US-12256738-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2025-03-25 US disclosed
US-20250008960-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-01-09 US disclosed
US-20230180761-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2023-06-15 US disclosed
US-11632957-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2023-04-25 US disclosed
US-20170339961-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-11-30 US disclosed
US-9781935-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-10-10 US disclosed
US-20160304522-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2016-10-20 US disclosed
US-20160304522-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2016-10-20 US disclosed
EP-1831198-B1 PYRIDINE CARBOXAMIDE DERIVATIVES FOR USE AS ANTICANCER AGENTS ASTRAZENECA AB (SE) 2009-04-08 EP disclosed
CN-101128454-A Pyridine carboxamide derivatives for use as anticancer agents ASTRAZENECA AB (SE) 2008-02-20 CN disclosed
CN-1440383-A PPAR gamma modulators SANKYO CO (JP) 2003-09-03 CN disclosed
US-20030134859-A1 PPAR-gamma modulator SANKYO COMPANY, LIMITED (JP) 2003-07-17 US disclosed
EP-1277729-A1 PPAR (GAMMA) MODULATORS Sankyo Company, Limited (JP) 2003-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11632957-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD SMN1; SMN2 3645/4885CYP3A4 933/4885MAPK1 2273/4885
US-20250134105-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD SMN1; SMN2 3645/4885CYP3A4 933/4885MAPK1 2273/4885
US-12256738-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD SMN1; SMN2 3645/4885CYP3A4 933/4885MAPK1 2273/4885
US-20250008960-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD SMN1; SMN2 3645/4885CYP3A4 933/4885MAPK1 2273/4885
US-20030130343-A1 Fat accumulation-modulating compounds FABP4, LIPC, PLIN1 SMN1; SMN2 3760/4885CYP3A4 2534/4885MAPK1 3233/4885
US-20030134859-A1 PPAR-gamma modulator PPARG, PPARA, PPARD SMN1; SMN2 3743/4885CYP3A4 1516/4885MAPK1 231/4885
US-20160304522-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD SMN1; SMN2 3645/4885CYP3A4 933/4885MAPK1 2273/4885
US-20230180761-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD SMN1; SMN2 3645/4885CYP3A4 933/4885MAPK1 2273/4885
US-20170339961-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD SMN1; SMN2 3645/4885CYP3A4 933/4885MAPK1 2273/4885
US-20250359552-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD SMN1; SMN2 3645/4885CYP3A4 933/4885MAPK1 2273/4885
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD SMN1; SMN2 3645/4885CYP3A4 933/4885MAPK1 2273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.