Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5907461 | 0.80 | LMNA (0.57) | ALDH1A1HSD17B10MAPTLMNACHRNB2 | |
| Diamide SCHEMBL5320404 | 0.78 | ALDH1A1 (0.65) | ALDH1A1TSHRNFKB1THPOHSD17B10 | |
| Butane SCHEMBL3151311 | 0.77 | LMNA (0.52) | ALDH1A1HSD17B10LMNACHRNB2CHRNB4 | |
| Butane SCHEMBL3150354 | 0.75 | LMNA (0.50) | ALDH1A1LMNACHRNB2CHRNB4CHRNA4 | |
| Butane SCHEMBL10560420 | 0.75 | LMNA (0.44) | ALDH1A1LMNACHRNB2CHRNB4CHRNA4 | |
| Bicarbonate SCHEMBL5374586 | 0.74 | LMNA (0.71) | ALDH1A1HSD17B10LMNA | |
| Bicarbonate SCHEMBL28895866 | 0.74 | LMNA (0.71) | ALDH1A1HSD17B10LMNA | |
| Acetone SCHEMBL590699 | 0.74 | LMNA (0.71) | ALDH1A1TSHRHSD17B10LMNA | |
| Bicarbonate SCHEMBL28942687 | 0.74 | LMNA (0.71) | ALDH1A1HSD17B10LMNA | |
| Diamide SCHEMBL1302348 | 0.74 | ALDH1A1 (0.77) | ALDH1A1TSHRNFKB1THPOHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794205-B1 | METHACRYLATE AMIDE ACETALS IN COATINGS | DU PONT (US) | 2012-06-13 | — | — | EP | disclosed |
| US-7608645-B2 | Use of (meth)acrylate functionalized amide acetals as reactive components with crosslinking agents and UV radiation; coating can be crosslinked by reaction with a crosslinker, such as isocyanate, and subsequently cured additionally by exposure to UV or electron beam (EB) energy; hardness, clarity | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-10-27 | — | — | US | disclosed |
| EP-1794166-B1 | POLYMERIC/OLIGOMERIC METHACRYLATE FUNCTIONALIZED AMIDE ACETALS IN COATINGS | DU PONT (US) | 2009-08-19 | — | — | EP | disclosed |
| US-7504459-B2 | Methacrylate amide acetals in coatings | E.I. DU PONT DE NEMOURS & COMPANY (US) | 2009-03-17 | — | — | US | disclosed |
| EP-1670840-B1 | PROCESS FOR MAKING AMIDE ACETALS | DU PONT (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1805185-A1 | HYDROXY AMIDE ACETALS AND THEIR USE IN COATINGS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1794166-A1 | POLYMERIC/OLIGOMERIC METHACRYLATE FUNCTIONALIZED AMIDE ACETALS IN COATINGS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-06-13 | — | — | EP | disclosed |
| EP-1794205-A1 | METHACRYLATE AMIDE ACETALS IN COATINGS | E.I. du Pont de Nemours & Company (US) | 2007-06-13 | — | — | EP | disclosed |
| US-7230112-B2 | Process for making amide acetals | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-06-12 | — | — | US | disclosed |
| US-7135530-B2 | Polymeric/oligomeric methacrylate functionalized amide acetals in coatings | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-11-14 | — | — | US | disclosed |
| EP-1670840-A1 | PROCESS FOR MAKING AMIDE ACETALS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-06-21 | — | — | EP | disclosed |
| US-20060128873-A1 | Dual cure coating compositions | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2006-06-15 | — | — | US | disclosed |
| WO-2006039618-A1 | POLYMERIC/OLIGOMERIC METHACRYLATE FUNCTIONALIZED AMIDE ACETALS IN COATINGS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-04-13 | — | — | WO | disclosed |
| WO-2006039619-A1 | HYDROXY AMIDE ACETALS AND THEIR USE IN COATINGS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-04-13 | — | — | WO | disclosed |
| WO-2006039617-A1 | METHACRYLATE AMIDE ACETALS IN COATINGS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-04-13 | — | — | WO | disclosed |
| US-20060069233-A1 | Polymeric/oligomeric methacrylate functionalized amide acetals in coatings | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2006-03-30 | — | — | US | disclosed |
| US-20060069205-A1 | Hydroxy amide acetals in coatings | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-03-30 | — | — | US | disclosed |
| US-20060069204-A1 | Methacrylate amide acetals in coatings | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2006-03-30 | — | — | US | disclosed |
| US-20050222425-A1 | Process for making amide acetals | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2005-10-06 | — | — | US | disclosed |
| WO-2005035613-A1 | PROCESS FOR MAKING AMIDE ACETALS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222425-A1 | Process for making amide acetals | NAAA, APEH, AMDHD2 | ALDH1A1 213/4885TSHR 4463/4885NFKB1 2536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.