SCHEMBL394357

SCHEMBL394357

C=C(c1ccccc1)C1CCCCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.45
ELANE P08246 1/20 0.45
HPGD P15428 1/20 0.44
KCNK3 O14649 1/20 0.41
KCNK9 Q9NPC2 1/20 0.41
RAB9A P51151 2/20 0.40
GAA P10253 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
MCL1 Q07820 1/20 0.39
SRD5A2 P31213 1/20 0.39
NPC1 O15118 1/20 0.39
CHRM2 P08172 1/20 0.38
CHRM1 P11229 1/20 0.38
JAK3 P52333 1/20 0.38
LMNA P02545 1/20 0.38
KMO O15229 1/20 0.38
KEAP1 Q14145 1/20 0.38
EPHX2 P34913 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5734309 1.00 POLB (0.45) POLBELANEHPGDKCNK3KCNK9
SCHEMBL1934073 0.98 ELANE (0.42) POLBELANEHPGDKCNK3KCNK9
SCHEMBL6858730 0.93 MTNR1A (0.41) POLBELANEHPGDKCNK3KCNK9
SCHEMBL4425242 0.91 ELANE (0.41) ELANEGAAHTT
SCHEMBL11704614 0.79 POLB (0.42) POLBELANEHPGDKCNK3KCNK9
SCHEMBL12064486 0.79 HRH3 (0.46) CHRM2CHRM1LMNA
SCHEMBL18905522 0.79 CHRM2 (0.40) POLBELANEHPGDRAB9AGAA
SCHEMBL12096955 0.78 POLB (0.41) POLBELANEHPGDKCNK3KCNK9
SCHEMBL10861677 0.77 GABBR2 (0.47) HPGDRAB9AGAAHTTSMN1; SMN2
SCHEMBL27936204 0.77 EPHX2 (0.45) RAB9AGAAHTTSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039195-A Preparation method of beta-thiocyanate alcohol derivative 山东省分析测试中心 2024-11-29 CN claimed
US-7220884-B2 Hydroaminomethylation of olefins DOW GLOBAL TECHNOLOGIES, INC. (US) 2007-05-22 US claimed
US-20050215825-A1 Hydroaminomethylation of olefins UNION CARBIDE CORPORATION 2005-09-29 US claimed
US-6825378-B2 TREATING CYCLOHEXYLPHENYL KETONE WITH YLIDE IN ANHYDROUS SOLVENT TO OBTAIN A-CYCLOHEXYLSTYRENE; DIHYDROXYLATION, OXIDATION COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-11-30 US claimed
US-20040192962-A1 Process for the synthesis of enantiomerically pure cyclohexylphenyl glycolic acid COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-09-30 US claimed
CN-119039195-A Preparation method of beta-thiocyanate alcohol derivative 山东省分析测试中心 2024-11-29 CN disclosed
US-12024590-B2 Resin composition, prepreg, film with resin, metal foil with resin, metal-clad laminate, and wiring board PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2024-07-02 US disclosed
US-12022611-B2 Prepreg, metal-clad laminate, and wiring board PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2024-06-25 US disclosed
US-11958951-B2 Resin composition, prepreg, resin-equipped film, resin-equipped metal foil, metal-cladded layered sheet, and wiring board PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2024-04-16 US disclosed
CN-117720787-A Flexible metal clad laminate and method of making the same 科腾聚合物荷兰有限责任公司 2024-03-19 CN disclosed
US-20240067810-A1 FLEXIBLE METAL CLAD LAMINATES AND METHODS OF PREPARATION THEREOF Kraton Corporation (US) 2024-02-29 US disclosed
CN-113061069-B Oxidative cleavage of compounds containing unsaturated double bonds 陈建添 2024-02-06 CN disclosed
US-20040192962-A1 Process for the synthesis of enantiomerically pure cyclohexylphenyl glycolic acid COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-09-30 US disclosed
US-20030187291-A1 Halogenation with iodine monochloride and iodine monobromide in an aqueous solution, forming a chemical intermediate for the preparation of indinavir, an HIV protease enzyme inhibitor MERCK SHARP & DOHME CORP. 2003-10-02 US disclosed
EP-1205517-A1 LOW-HYGROSCOPICITY LOW-BIREFRINGENCE RESIN COMPOSITIONS, MOLDING MATERIAL OBTAINED THEREFROM, SHEET OR FILM, AND OPTICAL PART HITACHI CHEMICAL COMPANY, LTD. (JP) 2002-05-15 EP disclosed
US-6372911-B1 REACTING COMPOUND CONTAINING AT LEAST ONE CARBON-CARBON DOUBLE BOND WITH CARBAMATE IN AQUEOUS SOLVENT IN PRESENCE OF BASE, OSMIUM CATALYST, CO-OXIDANT, AND OPTIONALLY ASYMMETRIC LIGAND, TO FORM REACTION MIXTURE CONTAINING BETA-HYDROXY CARBAMATE MERCK & CO., INC. 2002-04-16 US disclosed
EP-0732337-B1 Optically active asymmetric diphosphine and process for producing optically active substance in its presence TAKASAGO PERFUMERY CO LTD (JP) 2000-09-06 EP disclosed
US-5925893-A POLYESTERURETHANE IONOMER FUJI XEROX CO., LTD. (JP) 1999-07-20 US disclosed
US-5648548-A HYDROGENATION TAKASAGO INTERNATIONAL CORPORATION (JP) 1997-07-15 US disclosed
EP-0732337-A1 Optically active asymmetric diphosphine and process for producing optically active substance in its presence Takasago International Corporation (JP) 1996-09-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050215825-A1 Hydroaminomethylation of olefins HRH2, HRH4, HRH1 POLB 4584/4885ELANE 4367/4885HPGD 873/4885
US-20030187291-A1 Halogenation with iodine monochloride and iodine monobromide in an aqueous solution, forming a chemical intermediate for the preparation of indinavir, an HIV protease enzyme inhibitor IDE, MMP1, CYP3A4 POLB 379/4885ELANE 689/4885HPGD 1273/4885
US-20040192962-A1 Process for the synthesis of enantiomerically pure cyclohexylphenyl glycolic acid GRHPR, PGD, HPD POLB 2280/4885ELANE 4540/4885HPGD 444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.