Sugi Predict

Sugi Predict / Compounds / SCHEMBL394778

SCHEMBL394778

SCHEMBL394778

Cc1cc(C)c(C)c(N)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.56
▸ KDM4E B2RXH2 2/20 0.56
▸ LMNA P02545 1/20 0.56
▸ GAA P10253 1/20 0.56
▸ MAPT P10636 1/20 0.56
▸ TDP1 Q9NUW8 3/20 0.48
▸ TSHR P16473 3/20 0.45
▸ CYP3A4 P08684 4/20 0.43
▸ ALOX15 P16050 3/20 0.43
▸ TP53 P04637 1/20 0.43
▸ THRB P10828 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ MAPK1 P28482 1/20 0.41
▸ RAPGEF4 Q8WZA2 1/20 0.39
▸ HSD17B10 Q99714 3/20 0.39
▸ NOS3 P29474 1/20 0.39
▸ NOS1 P29475 1/20 0.39
▸ NOS2 P35228 1/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CASP7 P55210 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL868747 0.84 ALDH1A1 (0.53) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL1551822 0.77 RAPGEF4 (0.59) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL28951 0.77 RAPGEF4 (0.59) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL31141515 0.77 TDP1 (0.48) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL5175966 0.77 TDP1 (0.48) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL29568340 0.77 ALDH1A1 (0.56) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL360400 0.77 ALDH1A1 (0.56) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL14431315 0.74 ALDH1A1 (0.52) ALDH1A1KDM4ELMNAGAAMAPT
Hydrochloric Acid SCHEMBL3210344 0.74 ALDH1A1 (0.54) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL23009590 0.74 RAPGEF4 (0.50) ALDH1A1KDM4ELMNAGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192204-A Preparation method of fluoro aromatic hydrocarbon compound 阜新孚隆宝医药科技有限公司 2025-06-24 — — CN claimed
US-12071388-B2 Full continuous flow synthesis process of fluorine-containing aromatic hydrocarbon compounds Fujian Zhongxin Fluoride Material Gaobao Technology Co., Ltd. (CN) 2024-08-27 — — US claimed
WO-2022134489-A1 FULL CONTINUOUS FLOW SYNTHESIS PROCESS OF FLUORINE-CONTAINING AROMATIC HYDROCARBON COMPOUND 福建中欣氟材高宝科技有限公司 2022-06-30 — — WO claimed
US-20220204427-A1 FULL CONTINUOUS FLOW SYNTHESIS PROCESS OF FLUORINE-CONTAINING AROMATIC HYDROCARBON COMPOUNDS Fujian Zhongxin Fluoride Material Gaobao Technology Co., Ltd. (CN) 2022-06-30 — — US claimed
CN-112608212-B Full continuous flow synthesis process of fluorine-containing aromatic compound 福建中欣氟材高宝科技有限公司 2022-02-08 — — CN claimed
CN-112608212-A Full continuous flow synthesis process of fluorine-containing aromatic compound 福建高宝矿业有限公司 2021-04-06 — — CN claimed
CN-104743568-B A kind of synthetic method of 49 molecular sieves of MCM 中国石油化工股份有限公司 2017-03-29 — — CN claimed
CN-104743570-B A kind of synthetic method of MCM 56 molecular sieve 中国石油化工股份有限公司 2017-03-01 — — CN claimed
CN-103771435-B A kind of method of synthesizing MCM-22 molecular sieve SINOPEC CORP. (CN) 2015-10-28 — — CN claimed
CN-104743570-A A synthetic method of an MCM-56 molecular sieve CHINA PETROLEUM & CHEMICAL 2015-07-01 — — CN claimed
CN-104743568-A A synthetic method of an MCM-49 molecular sieve CHINA PETROLEUM & CHEMICAL 2015-07-01 — — CN claimed
CN-103771435-A Method for synthesis of MCM-22 molecular sieve CHINA PETROLEUM & CHEMICAL 2014-05-07 — — CN claimed
US-12071388-B2 Full continuous flow synthesis process of fluorine-containing aromatic hydrocarbon compounds Fujian Zhongxin Fluoride Material Gaobao Technology Co., Ltd. (CN) 2024-08-27 — — US disclosed
WO-2024141833-A1 THERMOPLASTIC COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLE COMPRISING THE COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-07-04 — — WO disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 — — US disclosed
US-20230242471-A1 THYROMIMETICS AUTOBAHN THERAPEUTICS, INC. 2023-08-03 — — US disclosed
US-4085268-A Disubstituted s-triazines ARMSTRONG CORK COMPANY (US) 1978-04-18 — — US disclosed
US-3975379-A METHINE BAYER AKTIENGESELLSCHAFT (DT) 1976-08-17 — — US disclosed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 — — US disclosed
US-3934019-A FUNGICIDE, INSECTICIDE, MITICIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-01-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 ALDH1A1 2814/4885KDM4E 4253/4885LMNA 692/4885
US-20220204427-A1 FULL CONTINUOUS FLOW SYNTHESIS PROCESS OF FLUORINE-CONTAINING AROMATIC HYDROCARBON COMPOUNDS AHR, FGFR2, FGFR1 ALDH1A1 1785/4885KDM4E 2623/4885LMNA 3301/4885
US-12071388-B2 Full continuous flow synthesis process of fluorine-containing aromatic hydrocarbon compounds AHR, FGFR2, FGFR1 ALDH1A1 1785/4885KDM4E 2623/4885LMNA 3301/4885
US-20230242471-A1 THYROMIMETICS TPO, THOP1, THRB ALDH1A1 1458/4885KDM4E 3392/4885LMNA 1814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.