Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 10/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897000 | 0.88 | P4HTM (0.59) | P4HTMLMNAKDM4ETSHRNFKB1 | |
| SCHEMBL14446852 | 0.86 | LMNA (0.43) | P4HTMLMNAKDM4ETSHRNFKB1 | |
| SCHEMBL5499533 | 0.83 | P4HTM (0.54) | P4HTMLMNAKDM4ETSHRNFKB1 | |
| SCHEMBL15858732 | 0.81 | MAPK1 (0.56) | P4HTMLMNAKDM4ETSHRNFKB1 | |
| SCHEMBL10174721 | 0.81 | PTGS1 (0.40) | P4HTMLMNAKDM4ETSHRNFKB1 | |
| SCHEMBL15858768 | 0.81 | PTGS1 (0.41) | P4HTMLMNAKDM4ETSHRNFKB1 | |
| SCHEMBL29852428 | 0.80 | KDM4E (0.52) | P4HTMLMNAKDM4ETSHRNFKB1 | |
| SCHEMBL286868 | 0.79 | KDM4E (0.69) | P4HTMLMNAKDM4ETSHRNFKB1 | |
| SCHEMBL25355779 | 0.79 | P4HTM (0.57) | P4HTMLMNAKDM4ETSHRNFKB1 | |
| SCHEMBL26008291 | 0.79 | P4HTM (0.57) | P4HTMLMNAKDM4ETSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022121844-A1 | DIHYDROPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海维申医药有限公司 | 2022-06-16 | — | — | WO | disclosed |
| US-10224487-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-03-05 | — | — | US | disclosed |
| US-10224487-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-03-05 | — | — | US | disclosed |
| US-9799839-B2 | Organometallic compound and organic light-emitting diode comprising the same | Samsung Diplay Co., Ltd. (KR) | 2017-10-24 | — | — | US | disclosed |
| US-9799839-B2 | Organometallic compound and organic light-emitting diode comprising the same | Samsung Diplay Co., Ltd. (KR) | 2017-10-24 | — | — | US | disclosed |
| US-9799839-B2 | Organometallic compound and organic light-emitting diode comprising the same | Samsung Diplay Co., Ltd. (KR) | 2017-10-24 | — | — | US | disclosed |
| US-9691992-B2 | Organic light-emitting diode | SAMSUNG DISPLEY CO., LTD. (KR) | 2017-06-27 | — | — | US | disclosed |
| US-9691992-B2 | Organic light-emitting diode | SAMSUNG DISPLEY CO., LTD. (KR) | 2017-06-27 | — | — | US | disclosed |
| US-9691992-B2 | Organic light-emitting diode | SAMSUNG DISPLEY CO., LTD. (KR) | 2017-06-27 | — | — | US | disclosed |
| US-20150076459-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2015-03-19 | — | — | US | disclosed |
| US-20090137547-A1 | Heterobicyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2009-05-28 | — | — | US | disclosed |
| US-20080249093-A1 | (3,4-Disubstituted)Propanoic Carboxylates as Sip (Edg) Receptor Agonists | MERCK & CO., INC. (US) | 2008-10-09 | — | — | US | disclosed |
| US-20080161300-A1 | Heterobicyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-07-03 | — | — | US | disclosed |
| US-20070155738-A1 | Heterobicyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS, INC. | 2007-07-05 | — | — | US | disclosed |
| US-20070155738-A1 | Heterobicyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS, INC. | 2007-07-05 | — | — | US | disclosed |
| US-20070155737-A1 | Heterobicyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS, INC. | 2007-07-05 | — | — | US | disclosed |
| US-20070155737-A1 | Heterobicyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS, INC. | 2007-07-05 | — | — | US | disclosed |
| CN-1894225-A | (3, 4-disubstituted) propanoates as sphingosine 1-phosphate (endothelial differentiation gene) receptor agonists | MERCK & CO INC (US) | 2007-01-10 | — | — | CN | disclosed |
| EP-1697333-A1 | (3,4-DISUBSTITUTED)PROPANOIC CARBOXYLATES AS S1P (EDG) RECEPTOR AGONISTS | Merck & Co., Inc. (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058848-A1 | (3,4-DISUBSTITUTED)PROPANOIC CARBOXYLATES AS S1P (EDG) RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155737-A1 | Heterobicyclic metalloprotease inhibitors | ADAMTS4, ADAMTS1, ADAMTS5 | P4HTM 390/4885LMNA 3275/4885KDM4E 418/4885 |
| US-20080161300-A1 | Heterobicyclic metalloprotease inhibitors | MMP13, TIMP3, MMP3 | P4HTM 726/4885LMNA 2387/4885KDM4E 2058/4885 |
| US-20090137547-A1 | Heterobicyclic metalloprotease inhibitors | MMP13, TIMP3, MMP3 | P4HTM 726/4885LMNA 2387/4885KDM4E 2058/4885 |
| US-20080249093-A1 | (3,4-Disubstituted)Propanoic Carboxylates as Sip (Edg) Receptor Agonists | S1PR1, S1PR3, S1PR5 | P4HTM 2090/4885LMNA 3260/4885KDM4E 2051/4885 |
| US-20070155738-A1 | Heterobicyclic metalloprotease inhibitors | MMP13, TIMP3, MMP3 | P4HTM 726/4885LMNA 2387/4885KDM4E 2058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.