SCHEMBL3953836

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17321404	0.89	PRKAG1 (0.58)	FLT3CDK2PRKAG1PRKAA1PRKAB1
	SCHEMBL18554248	0.84	BCHE (0.56)	FLT3CDK2PRKAG1PRKAA1PRKAB1
	SCHEMBL176882	0.84	PRKAG1 (0.66)	FLT3CDK2PRKAG1PRKAA1PRKAB1
	SCHEMBL13069602	0.82	JAK2 (0.51)	FLT3CDK2PRKAG1PRKAA1PRKAB1
	SCHEMBL16516393	0.82	KDM4E (0.63)	FLT3CDK2PRKAG1PRKAA1PRKAB1
	SCHEMBL12583303	0.80	YTHDC1 (0.60)	FLT3CDK2PRKAG1PRKAA1PRKAB1
	SCHEMBL4012655	0.80	PRKAG1 (0.48)	FLT3CDK2PRKAG1PRKAA1PRKAB1
	SCHEMBL6920155	0.80	PRKAB2 (0.39)	FLT3CDK2PRKAG1PRKAA1PRKAB1
	SCHEMBL3953831	0.79	PRKAG1 (0.47)	FLT3CDK2PRKAG1PRKAA1PRKAB1
	SCHEMBL10073863	0.78	CYP1A2 (0.50)	FLT3CDK2PRKAG1PRKAA1PRKAB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.