SCHEMBL396052

SCHEMBL396052

C=CC(=O)NCc1ccc(S(=O)(=O)N(CC)CC)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
NAMPT P43490 2/20 0.54
TGM2 P21980 1/20 0.54
SMN1; SMN2 Q16637 4/20 0.49
POLB P06746 1/20 0.49
LMNA P02545 5/20 0.49
HTT P42858 3/20 0.49
KMT2A Q03164 2/20 0.48
MAPK1 P28482 1/20 0.47
CA12 O43570 1/20 0.47
CA9 Q16790 1/20 0.47
NPSR1 Q6W5P4 2/20 0.47
GAA P10253 2/20 0.47
MEN1 O00255 1/20 0.47
THRB P10828 1/20 0.47
PPARG P37231 1/20 0.47
NCOA2 Q15596 1/20 0.47
NCOA1 Q15788 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL437691 0.86 ALDH1A1 (0.57) ALDH1A1NAMPTTGM2SMN1; SMN2POLB
SCHEMBL397215 0.84 POLB (0.60) ALDH1A1NAMPTSMN1; SMN2POLBLMNA
SCHEMBL1869837 0.80 TGM2 (0.63) ALDH1A1NAMPTTGM2SMN1; SMN2POLB
SCHEMBL2723034 0.79 TGM2 (0.63) ALDH1A1TGM2SMN1; SMN2POLBLMNA
SCHEMBL393582 0.79 ALDH1A1 (0.57) ALDH1A1TGM2LMNAHTTKMT2A
SCHEMBL394379 0.78 TGM2 (0.58) ALDH1A1NAMPTTGM2SMN1; SMN2KMT2A
SCHEMBL732934 0.78 TGM2 (0.81) ALDH1A1TGM2LMNAKMT2AMAPK1
SCHEMBL202717 0.78 CA1 (0.62) ALDH1A1TGM2SMN1; SMN2POLBKMT2A
SCHEMBL5681005 0.78 TGM2 (0.61) ALDH1A1TGM2SMN1; SMN2POLBLMNA
SCHEMBL398016 0.77 NAMPT (0.55) ALDH1A1NAMPTTGM2SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2012-06-14 US disclosed
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
EP-1972440-B1 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM CORP (JP) 2010-06-23 EP disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed
US-20080233516-A1 NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
EP-1972440-A2 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM Corporation (JP) 2008-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE EIF3L, EIF2B1, EIF2B5 ALDH1A1 1302/4885NAMPT 2262/4885TGM2 3496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.