SCHEMBL437691

SCHEMBL437691

C=CC(=O)NCc1ccc(S(=O)(=O)N(C)C)cc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.57
TGM2 P21980 2/20 0.56
NAMPT P43490 2/20 0.52
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
SMN1; SMN2 Q16637 1/20 0.48
TSHR P16473 1/20 0.48
POLB P06746 1/20 0.46
NPSR1 Q6W5P4 1/20 0.45
LMNA P02545 2/20 0.44
PKM P14618 2/20 0.43
NR2F2 P24468 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA14 Q9ULX7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396052 0.86 ALDH1A1 (0.61) ALDH1A1TGM2NAMPTMEN1KMT2A
SCHEMBL397454 0.83 RAB9A (0.52) ALDH1A1TGM2NAMPTMEN1KMT2A
SCHEMBL15669425 0.83 ALDH1A1 (0.61) ALDH1A1NAMPTMEN1KMT2ASMN1; SMN2
SCHEMBL20489122 0.81 ALDH1A1 (0.67) ALDH1A1NAMPTMEN1KMT2ASMN1; SMN2
SCHEMBL2723034 0.81 TGM2 (0.63) ALDH1A1TGM2MEN1KMT2ASMN1; SMN2
SCHEMBL3817703 0.81 TGM2 (0.49) ALDH1A1TGM2NAMPTMEN1KMT2A
SCHEMBL394379 0.81 TGM2 (0.58) ALDH1A1TGM2NAMPTMEN1KMT2A
SCHEMBL732934 0.80 TGM2 (0.81) ALDH1A1TGM2MEN1KMT2ATSHR
SCHEMBL202717 0.80 CA1 (0.62) ALDH1A1TGM2MEN1KMT2ASMN1; SMN2
SCHEMBL5681005 0.80 TGM2 (0.61) ALDH1A1TGM2MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2012-06-14 US disclosed
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
EP-1972440-B1 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM CORP (JP) 2010-06-23 EP disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20080233516-A1 NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
EP-1972440-A2 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM Corporation (JP) 2008-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE EIF3L, EIF2B1, EIF2B5 ALDH1A1 1302/4885TGM2 3496/4885NAMPT 2262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.