SCHEMBL397215

SCHEMBL397215

C=CC(=O)NCc1cccc(S(=O)(=O)N(CC)CC)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.60
ALDH1A1 P00352 7/20 0.50
SMN1; SMN2 Q16637 5/20 0.50
TSHR P16473 2/20 0.50
MAPK1 P28482 2/20 0.49
LMNA P02545 5/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
HPGD P15428 2/20 0.46
GAA P10253 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
BTK Q06187 1/20 0.46
ITK Q08881 1/20 0.46
MAPT P10636 3/20 0.46
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
HTT P42858 2/20 0.45
HSP90AA1 P07900 1/20 0.45
RAB9A P51151 1/20 0.45
USP2 O75604 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL397454 0.87 RAB9A (0.52) POLBALDH1A1SMN1; SMN2LMNAKMT2A
SCHEMBL396052 0.84 ALDH1A1 (0.61) POLBALDH1A1SMN1; SMN2MAPK1LMNA
SCHEMBL393849 0.81 ALDH1A1 (0.47) ALDH1A1LMNABTKHTTRAB9A
SCHEMBL393894 0.81 FBP1 (0.49) POLBALDH1A1GAABTKHTT
SCHEMBL396034 0.80 ALDH1A1 (0.49) POLBALDH1A1KMT2AMEN1GAA
SCHEMBL394316 0.79 FBP1 (0.45) ALDH1A1LMNAKMT2AHTTUSP2
SCHEMBL397556 0.78 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2GAABTKMAPT
SCHEMBL732581 0.78 TGM2 (0.61) POLBALDH1A1TSHRMAPK1LMNA
SCHEMBL7751005 0.78 CCR1 (0.48) ALDH1A1NPSR1BTKKDM4EHTT
SCHEMBL397300 0.78 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2LMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2012-06-14 US disclosed
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
EP-1972440-B1 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM CORP (JP) 2010-06-23 EP disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed
US-20080233516-A1 NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
EP-1972440-A2 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM Corporation (JP) 2008-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE EIF3L, EIF2B1, EIF2B5 POLB 3689/4885ALDH1A1 1302/4885SMN1; SMN2 815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.