Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | AGXT | P21549 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795851 | 0.84 | IDO1 (0.61) | IDO1AGXTTDP1CA1CA2 | |
| SCHEMBL8075893 | 0.84 | IDO1 (0.61) | IDO1AGXTTDP1CA1CA2 | |
| SCHEMBL5795848 | 0.84 | IDO1 (0.61) | IDO1AGXTTDP1CA1CA2 | |
| Formic Acid SCHEMBL6366129 | 0.82 | IDO1 (0.53) | IDO1AGXTTDP1NPC1RAB9A | |
| SCHEMBL9715527 | 0.81 | TDP1 (0.50) | IDO1AGXTTDP1NPC1RAB9A | |
| SCHEMBL1195343 | 0.81 | CA1 (0.45) | IDO1AGXTTDP1NPC1RAB9A | |
| SCHEMBL1195340 | 0.81 | CA1 (0.45) | IDO1AGXTTDP1NPC1RAB9A | |
| SCHEMBL34413 | 0.81 | IDO1 (0.67) | IDO1AGXTTDP1CA1CA2 | |
| SCHEMBL12815347 | 0.81 | ALDH1A1 (0.60) | IDO1AGXTTDP1CA1CA2 | |
| SCHEMBL14952744 | 0.80 | AGXT (0.48) | IDO1AGXTNPC1RAB9ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3953341-A1 | NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI | PI Industries Ltd. (IN) | 2022-02-16 | — | — | EP | claimed |
| WO-2020208511-A1 | NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LIMITED (IN) | 2020-10-15 | — | — | WO | claimed |
| US-20240228495-A1 | Tricyclic Inhibitors of Influenza Virus Endonuclease | STANFORD RES INST INT (US) | 2024-07-11 | — | — | US | disclosed |
| EP-3953341-A1 | NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI | PI Industries Ltd. (IN) | 2022-02-16 | — | — | EP | disclosed |
| CN-110734456-A | compounds, preparation method and medical application thereof | 南京谷睿生物科技有限公司 | 2020-01-31 | — | — | CN | disclosed |
| US-10292936-B2 | Modified alginates for cell encapsulation and cell therapy | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-05-21 | — | — | US | disclosed |
| US-20170239190-A1 | MODIFIED ALGINATES FOR CELL ENCAPSULATION AND CELL THERAPY | THE CHILDREN'S MEDICAL CENTER CORPORATION | 2017-08-24 | — | — | US | disclosed |
| EP-2792675-B1 | COMPOUND AND ASYMMETRIC SYNTHESIS REACTION | MICROBIAL CHEM RES FOUND (JP) | 2017-04-12 | — | — | EP | disclosed |
| EP-2792675-B1 | COMPOUND AND ASYMMETRIC SYNTHESIS REACTION | MICROBIAL CHEM RES FOUND (JP) | 2017-04-12 | — | — | EP | disclosed |
| US-9187498-B2 | Compound and asymmetric synthesis reaction | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2015-11-17 | — | — | US | disclosed |
| US-20150183807-A1 | Compound and Asymmetric Synthesis Reaction | MICROBIAL CHEM RES FOUND (JP) | 2015-07-02 | — | — | US | disclosed |
| US-6211370-B1 | REACTING A DIENOPHILE WITH A 1,3-DIENE | HARVARD UNIVERSITY | 2001-04-03 | — | — | US | disclosed |
| JP-2001011007-A | PRODUCTION OF BENZYLOXYACETALDEHYDE COMPOUND | SUMIKA FINE CHEMICALS CO LTD | 2001-01-16 | — | — | JP | disclosed |
| WO-2001002333-A1 | PROCESS FOR PREPARING BENZYLOXYACETALDEHYDE COMPOUNDS | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2001-01-11 | — | — | WO | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-6130340-A | CATALYST SELECTIVITY; DRUG CHEMICAL INTERMEDIATES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-10-10 | — | — | US | disclosed |
| WO-2000050365-A1 | ASYMMETRIC CYCLOADDITION REACTIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-08-31 | — | — | WO | disclosed |
| WO-1999036375-A1 | ASYMMETRIC CYCLOADDITION REACTIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1999-07-22 | — | — | WO | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10292936-B2 | Modified alginates for cell encapsulation and cell therapy | ALG1, CD44, CD47 | IDO1 2301/4885AGXT 775/4885TDP1 3611/4885 |
| US-20240228495-A1 | Tricyclic Inhibitors of Influenza Virus Endonuclease | RNASEH1, RNASEL, DNASE1 | IDO1 42/4885AGXT 1794/4885TDP1 49/4885 |
| US-20150183807-A1 | Compound and Asymmetric Synthesis Reaction | CYP2E1, REV1, CYP19A1 | IDO1 2100/4885AGXT 264/4885TDP1 3979/4885 |
| US-20170239190-A1 | MODIFIED ALGINATES FOR CELL ENCAPSULATION AND CELL THERAPY | ALG1, CD44, CD47 | IDO1 2301/4885AGXT 775/4885TDP1 3611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.