Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8223667 | 0.77 | SLC6A3 (0.47) | SLC6A2SLC6A3KDM1AGAAHTR2A | |
| SCHEMBL1741490 | 0.69 | SLC6A2 (0.53) | SLC6A2SLC6A3HTR3APRCPCHRNA7 | |
| SCHEMBL7369414 | 0.69 | SLC6A2 (0.34) | SLC6A2SLC6A3HTR3A | |
| SCHEMBL1069753 | 0.66 | SLC6A3 (0.48) | SLC6A2SLC6A3HTR3APRCPCHRNA7 | |
| SCHEMBL7110912 | 0.64 | HTR3A (0.47) | SLC6A2SLC6A3HTR3APRCPCHRNA7 | |
| SCHEMBL170771 | 0.62 | HTR3A (0.50) | SLC6A2SLC6A3HTR3APRCPCHRNA7 | |
| SCHEMBL11659016 | 0.61 | LMNA (0.42) | SLC6A2SLC6A3HTR3ACHRNA7SLC6A4 | |
| SCHEMBL28909423 | 0.60 | MECP2 (0.33) | HTR3ALMNACYP2A6 | |
| SCHEMBL20458673 | 0.60 | LMNA (0.57) | HTR3ALMNACYP2A6HTR2AHTR2C | |
| SCHEMBL16398624 | 0.60 | ALOX15 (0.38) | SLC6A2SLC6A3HTR3ASLC6A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037350-A2 | DIKETOPYRROLO[3,4-c]PYRROLE THIOL/DISULFIDE DYE, COMPOSITION COMPRISING THIS DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-03-26 | — | — | WO | disclosed |