Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291728 | 0.70 | SLC6A4 (0.44) | — | |
| SCHEMBL3966012 | 0.69 | SLC6A2 (0.42) | SLC6A2SLC6A3HTR3A | |
| SCHEMBL1741490 | 0.60 | SLC6A2 (0.53) | SLC6A2SLC6A3HTR3A | |
| SCHEMBL11628812 | 0.59 | SLC6A3 (0.56) | SLC6A2SLC6A3HTR3A | |
| SCHEMBL1069753 | 0.57 | SLC6A3 (0.48) | SLC6A2SLC6A3HTR3A | |
| SCHEMBL7110912 | 0.55 | HTR3A (0.47) | SLC6A2SLC6A3HTR3A | |
| SCHEMBL16398624 | 0.55 | ALOX15 (0.38) | SLC6A2SLC6A3HTR3A | |
| SCHEMBL16398622 | 0.55 | ALOX15 (0.38) | SLC6A2SLC6A3HTR3A | |
| SCHEMBL6582897 | 0.54 | HTR2C (0.63) | SLC6A2SLC6A3 | |
| SCHEMBL170771 | 0.54 | HTR3A (0.50) | SLC6A2SLC6A3HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137889-A | Hypotensive agents; coronary vasodilators; calcium antagonists; antiinflammatory agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-5034395-A | Hypotensive agents, carboxylated dihydropyridines | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |