Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | FOS | P01100 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3969449 | 0.87 | ALOX5 (0.41) | ALOX5CYP2C19GAAMAPTCYP3A4 | |
| SCHEMBL6535506 | 0.86 | GAA (0.33) | CYP1A2CYP2D6CYP2C19GAATHRB | |
| SCHEMBL3975247 | 0.82 | TDP1 (0.46) | ALOX5GAAMAPTCYP3A4PDE10A | |
| SCHEMBL3968067 | 0.81 | CYP3A4 (0.42) | ALOX5CYP2C19MAPTLMNACYP3A4 | |
| SCHEMBL3970430 | 0.76 | PDE10A (0.42) | ALOX5GAAMAPTLMNACYP3A4 | |
| SCHEMBL3965393 | 0.72 | KDM4E (0.43) | ALOX5GAAMAPTLMNACA1 | |
| SCHEMBL8140503 | 0.72 | PDE10A (0.45) | ALOX5CYP2C19GAAMAPTCYP3A4 | |
| SCHEMBL3977541 | 0.71 | CHRNB4 (0.38) | ALOX5LMNAHTTALDH1A1MEN1 | |
| SCHEMBL6535756 | 0.71 | TDP1 (0.39) | GAAMAPTCYP3A4ALDH1A1MEN1 | |
| SCHEMBL3968161 | 0.68 | PDE10A (0.39) | ALOX5CA1CA2PDE10ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359890-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2009-08-12 | — | — | EP | disclosed |
| US-6673934-B2 | 4-AMINO-2-(1-ARYLOXY-ETHYL)PHENOL COMPOUND | THE PROCTER & GAMBLE COMPANY | 2004-01-06 | — | — | US | disclosed |
| EP-1359890-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20020157192-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-31 | — | — | US | disclosed |
| WO-2002058631-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020157192-A1 | Primary intermediates for oxidative coloration of hair | AOX1, CYC1, CBR1 | ALOX5 276/4885CYP1A2 150/4885CYP2D6 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.