Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979633 | 0.80 | POLB (0.43) | HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL3973213 | 0.80 | HTR2A (0.42) | HRH3SMN1; SMN2CYP2D6CYP2C9TSHR | |
| SCHEMBL3974894 | 0.79 | HTR2A (0.44) | ACHEHRH3HTR2CSMN1; SMN2CYP2D6 | |
| SCHEMBL4081651 | 0.77 | LMNA (0.46) | HSD17B10CYP2D6CYP2C9TSHR | |
| SCHEMBL3973494 | 0.76 | IDH1 (0.39) | HSD17B10SMN1; SMN2TSHRCA1CA2 | |
| SCHEMBL3972272 | 0.74 | CA1 (0.38) | ACHECA1CA2CA4CA6 | |
| SCHEMBL3973824 | 0.74 | HTR2A (0.36) | SMN1; SMN2CA1CA2CA4CA6 | |
| SCHEMBL4084541 | 0.73 | SYK (0.45) | HSD17B10MAPTSMN1; SMN2CYP2D6TSHR | |
| SCHEMBL438402 | 0.73 | HDAC1 (0.42) | — | |
| SCHEMBL3974167 | 0.73 | BCHE (0.39) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |