SCHEMBL3975178

SCHEMBL3975178

CN(C)c1ccc(C([O])=O)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.70
MAPT P10636 4/20 0.70
HPGD P15428 3/20 0.70
NPC1 O15118 5/20 0.59
RAB9A P51151 4/20 0.59
ALOX15 P16050 2/20 0.55
TSHR P16473 2/20 0.55
HSD17B10 Q99714 1/20 0.55
MAPK1 P28482 2/20 0.54
CYP3A4 P08684 1/20 0.54
HBB P68871 1/20 0.54
KMT2A Q03164 5/20 0.53
MEN1 O00255 4/20 0.53
HDAC1 Q13547 3/20 0.53
HDAC6 Q9UBN7 3/20 0.53
POLB P06746 2/20 0.53
KDM4E B2RXH2 2/20 0.53
TDP1 Q9NUW8 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.47
TP53 P04637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194888 0.82 RAB9A (0.83) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL36517 0.82 ALDH1A1 (1.00) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL274966 0.82 ALDH1A1 (1.00) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL12432243 0.80 ALDH1A1 (0.70) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL11758312 0.80 ALDH1A1 (0.95) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL1396486 0.80 ALDH1A1 (0.95) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL33368 0.80 NPC1 (0.77) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL10001067 0.80 RAB9A (0.77) ALDH1A1MAPTHPGDNPC1RAB9A
Michler'S Ketone SCHEMBL6566205 0.80 ALDH1A1 (0.95) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL60627 0.80 RAB9A (0.77) ALDH1A1MAPTHPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104395275-B copolymerizable photoinitiators 意大利艾坚蒙树脂有限公司 2016-08-24 CN disclosed
US-9285679-B2 Actinic ray-sensitive or radiation-sensitive composition, and resist film, resist-coated mask blanks, resist pattern forming method and photomask each using the composition FUJIFILM CORPORATION (JP) 2016-03-15 US disclosed
US-20150010855-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE COMPOSITION, AND RESIST FILM, RESIST-COATED MASK BLANKS, RESIST PATTERN FORMING METHOD AND PHOTOMASK EACH USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2015-01-08 US disclosed
US-7514452-B2 2-furancarboxylic acid hydrazides and pharmaceutical compositions containing the same DAINIPPON PHARMACEUTICAL CO., LTD (JP) 2009-04-07 US disclosed
US-20050171196-A1 2-Furancarboxylic acid hydrazides and pharmaceutical compositions containing the same DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2005-08-04 US disclosed
EP-1489077-A1 2-FURANCARBOXYLIC ACID HYDRAZIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 2004-12-22 EP disclosed
US-3936462-A CNS DEPRESSANT, ANALGESIC STERLING DRUG INC. (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050171196-A1 2-Furancarboxylic acid hydrazides and pharmaceutical compositions containing the same GLP1R, GCGR, GPR119 ALDH1A1 1389/4885MAPT 4833/4885HPGD 299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.