Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397628 | 0.86 | HPGD (0.56) | HPGDLMNAHTTSMN1; SMN2AR | |
| SCHEMBL1421898 | 0.83 | HPGD (0.65) | HPGDLMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL398544 | 0.82 | ADRA2A (0.47) | HPGDLMNAHTTSMN1; SMN2AR | |
| SCHEMBL397676 | 0.79 | HDAC1 (0.68) | LMNAARHDAC1HDAC8ALDH1A1 | |
| SCHEMBL4161796 | 0.79 | HPGD (0.62) | HPGDLMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL397357 | 0.79 | ALDH1A1 (0.64) | HPGDLMNASMN1; SMN2MAPTHDAC1 | |
| SCHEMBL16799573 | 0.78 | HPGD (0.61) | HPGDLMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL3426193 | 0.77 | CA2 (0.46) | HPGDLMNAHTTGAAALDH1A1 | |
| SCHEMBL396740 | 0.76 | HDAC1 (0.59) | LMNAHDAC1HDAC8GAAALDH1A1 | |
| SCHEMBL6442701 | 0.76 | ALDH1A1 (0.52) | HPGDLMNASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101332-B2 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | FUJIFILM CORPORATION (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20090246688-A1 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |
| EP-2105298-A1 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | Fujifilm Corporation (JP) | 2009-09-30 | — | — | EP | disclosed |