Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.53 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.53 |
| ▸ | PI4KA | P42356 | 2/20 | 0.53 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.53 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.53 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.53 |
| ▸ | GAPDH | P04406 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | STAT6 | P42226 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL23802568 | 0.94 | ADORA1 (0.50) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL10365538 | 0.87 | SLC29A1 (0.39) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL31062627 | 0.85 | ADORA3 (0.55) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL481525 | 0.85 | ADORA3 (0.55) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL5024893 | 0.84 | ADORA3 (0.54) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL454216 | 0.84 | ADORA3 (0.54) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| Water SCHEMBL27885621 | 0.84 | ADORA3 (0.54) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL23042807 | 0.84 | ADORA3 (0.54) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL1417403 | 0.84 | ADORA3 (0.54) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B | |
| SCHEMBL27657118 | 0.84 | ADORA3 (0.54) | ADORA3ADORA2ASLC28A1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1639182-A | Synthesis method of 5 '-deoxy-5' -chloroadenosine and 5 '-deoxy-5' -methylthioadenosine | PFIZER (US) | 2005-07-13 | — | — | CN | claimed |
| EP-1483279-A1 | PROCESSES FOR THE SYNTHESIS OF 5'-DEOXY-5'-CHLOROADENOSINE AND 5'-DEOXY-5'-METHYLTHIOADENOSINE | PFIZER INC. (US) | 2004-12-08 | — | — | EP | claimed |
| US-20030181713-A1 | Processes for the synthesis of chloroadenosine and methylthioadenosine | SRIRANGAM JAYARAM KASTURI (US) | 2003-09-25 | — | — | US | claimed |
| WO-2003074541-A1 | PROCESSES FOR THE SYNTHESIS OF 5’-DEOXY-5’ CHLOROADENOSINE AND 5’-DEOXY-5’METHYLTHIOADENOSINE | PFIZER INC. (US) | 2003-09-12 | — | — | WO | claimed |
| US-20020177695-A1 | Nucleic acid probes and methods | DUKE UNIVERSITY | 2002-11-28 | — | — | US | claimed |
| US-6288221-B1 | REPLACING NUCLEOSIDE WITH DIMETHOXYTRITYL, PHOSPHORAMIDITE, OR HALONUCLEOSIDE DERIVATIVE; ELECTROCHEMICAL OR PHOTOCHEMICAL DETECTION OF NUCLEIC ACID SEQUENCES | DUKE UNIVERSITY | 2001-09-11 | — | — | US | claimed |
| JP-5255378-A | — | — | None | — | — | JP | disclosed |
| JP-61171423-A | — | — | None | — | — | JP | disclosed |
| US-12551475-B2 | Methods and compositions for treating RNA viral infections | MODEL MEDICINES, INC. (US) | 2026-02-17 | — | — | US | disclosed |
| US-12516080-B2 | Remdesivir and remdesivir analogs, solutions, and nanoparticle, liposomal, and microparticle compositions for treating viral infections | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2026-01-06 | — | — | US | disclosed |
| EP-4667008-A2 | METHODS AND COMPOSITIONS FOR TREATING RNA VIRAL INFECTIONS | Model Medicines, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| US-20250017936-A1 | CELL-POTENT BISUBSTRATE INHIBITORS FOR NICOTINAMIDE N-METHYLTRANSFERASE (NNMT) AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2025-01-16 | — | — | US | disclosed |
| EP-4436566-A1 | CELL-POTENT BISUBSTRATE INHIBITORS FOR NICOTINAMIDE N-METHYLTRANSFERASE (NNMT) AND USES THEREOF | Purdue Research Foundation (US) | 2024-10-02 | — | — | EP | disclosed |
| EP-0390112-A2 | Selective adenosine receptor agents | MERRELL PHARMACEUTICALS INC. (US) | 1990-10-03 | — | — | EP | disclosed |
| EP-0390111-A2 | Selective adenosine receptor compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-10-03 | — | — | EP | disclosed |
| EP-0269574-A2 | Novel adenosine derivatives and pharmaceutical compositions containing them as an active ingredient | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |
| EP-0253962-A2 | Use of adenosine derivatives as anti-dementia agents | HOECHST JAPAN LIMITED (JP) | 1988-01-27 | — | — | EP | disclosed |
| JP-S61171423-A | DRUG FOR ALLEVIATING DENTAL CARIES AND PERIODONTOSIS | ADVANCE RES & DEV CO LTD | 1986-08-02 | — | — | JP | disclosed |
| CN-85108658-A | N 6The manufacture method that replaces ribodesose adenyhomotype thing | — | 1986-07-16 | — | — | CN | disclosed |
| US-4376116-A | TREATMENT OF CYSTIC FIBROSIS AND PARASITIC INFECTIONS | RESEARCH CORPORATION (US) | 1983-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250017936-A1 | CELL-POTENT BISUBSTRATE INHIBITORS FOR NICOTINAMIDE N-METHYLTRANSFERASE (NNMT) AND USES THEREOF | NNMT, NAMPT, NNT | ADORA3 3333/4885ADORA2A 3317/4885SLC28A1 35/4885 |
| US-12551475-B2 | Methods and compositions for treating RNA viral infections | SARS1, EIF2AK2, SNRPE | ADORA3 438/4885ADORA2A 913/4885SLC28A1 587/4885 |
| US-20020177695-A1 | Nucleic acid probes and methods | NUDT1, NT5C3B, NT5C2 | ADORA3 80/4885ADORA2A 229/4885SLC28A1 152/4885 |
| US-20030181713-A1 | Processes for the synthesis of chloroadenosine and methylthioadenosine | MTAP, ADAR, NUDT1 | ADORA3 80/4885ADORA2A 37/4885SLC28A1 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.