Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23334741 | 0.96 | TP53 (0.57) | HPGDTP53KDM4EMAPTNPC1 | |
| SCHEMBL20892324 | 0.78 | HPGD (0.55) | HPGDTP53KDM4EMAPTNPC1 | |
| SCHEMBL15778999 | 0.76 | SMN1; SMN2 (0.75) | HPGDTP53KDM4EMAPTNPC1 | |
| SCHEMBL23335496 | 0.74 | TP53 (0.51) | HPGDTP53KDM4EMAPTNPC1 | |
| SCHEMBL1857150 | 0.74 | TP53 (0.38) | HPGDTP53KDM4EMAPTNPC1 | |
| SCHEMBL22336162 | 0.74 | HPGD (0.51) | HPGDTP53KDM4EMAPTNPC1 | |
| SCHEMBL1856215 | 0.73 | TP53 (0.36) | HPGDTP53KDM4EMAPTNPC1 | |
| SCHEMBL23334742 | 0.73 | CES1 (0.38) | HPGDTP53KDM4EMAPTNPC1 | |
| SCHEMBL1854014 | 0.73 | S1PR1 (0.37) | HPGDTP53KDM4EMAPTNPC1 | |
| SCHEMBL11085849 | 0.72 | MAPT (0.49) | HPGDTP53KDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642741-A | Functionalized benzamide derivatives as antiviral agents against HBV infection | 巴鲁克斯布隆伯格研究所 | 2020-01-03 | — | — | CN | claimed |
| US-20150307443-A1 | FUNCTIONALIZED BENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | BARUCH S BLUMBERG INST (US) | 2015-10-29 | — | — | US | claimed |
| EP-2928459-A2 | FUNCTIONALIZED BENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | Baruch S. Blumberg Institute (US) | 2015-10-14 | — | — | EP | claimed |
| WO-2014089296-A2 | FUNCTIONALIZED BENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | INSTITUTE FOR HEPATITIS AND VIRUS RESEARCH (US) | 2014-06-12 | — | — | WO | claimed |
| EP-4640806-A1 | WATER-SOLUBLE AUTOMATIC DISHWASHING DETERGENT POUCH | The Procter & Gamble Company (US) | 2025-10-29 | — | — | EP | disclosed |
| US-20250326994-A1 | WATER-SOLUBLE AUTOMATIC DISHWASHING DETERGENT POUCH | PROCTER & GAMBLE (US) | 2025-10-23 | — | — | US | disclosed |
| WO-2025097104-A1 | THIENYL COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI DRUG DISCOVERY LLC (US) | 2025-05-08 | — | — | WO | disclosed |
| CN-118557574-A | Dihydroisoxazole compounds for controlling sea lice | 瑞士伊兰科动物保健有限公司 | 2024-08-30 | — | — | CN | disclosed |
| EP-3466946-B1 | THIOPHENE, MANUFACTURING METHOD THEREOF, AND PHARMACEUTICAL APPLICATION OF SAME | DONGBAO PURPLE STAR HANGZHOU BIOPHARMACEUTICAL CO LTD (CN) | 2023-08-30 | — | — | EP | disclosed |
| WO-2021083182-A1 | URICOSURIC AGENT, SYNTHETIC METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 南京明德新药研发有限公司 | 2021-05-06 | — | — | WO | disclosed |
| US-10829483-B2 | Thiophene, manufacturing method thereof, and pharmaceutical application of same | CSTONE PHARMACEUTICAL (SUZHOU) CO., LTD. (CN) | 2020-11-10 | — | — | US | disclosed |
| US-20200140423-A1 | Thiophene, Manufacturing Method Thereof, And Pharmaceutical Application Of Same | DONGBAO PURPLE STAR (HANGZHOU) BIOPHARMACEUTICAL CO., LTD (CN) | 2020-05-07 | — | — | US | disclosed |
| EP-1296972-B1 | ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS | AVENTIS PHARMA INC (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2009060030-A1 | HETEROARYL-SUBSTITUTED 2-PYRIDINYLMETHYLAMINE DERIVATIVES | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2009-05-14 | — | — | WO | disclosed |
| EP-2058306-A1 | Heteroaryl-substituted 2-pyridinyl-methylamine derivatives | SCHWARZ PHARMA AG (DE) | 2009-05-13 | — | — | EP | disclosed |
| US-6977263-B2 | Chemical compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2005-12-20 | — | — | US | disclosed |
| US-20050228018-A1 | Chemical compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2005-10-13 | — | — | US | disclosed |
| US-20030187020-A1 | Chemical compounds | AVENTISUB LLC | 2003-10-02 | — | — | US | disclosed |
| EP-1296972-A1 | ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS | Aventis Pharmaceuticals Inc. (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2001090101-A1 | ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307443-A1 | FUNCTIONALIZED BENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | HAVCR2, PHB2, PHB1 | HPGD 2075/4885TP53 2170/4885KDM4E 1371/4885 |
| US-10829483-B2 | Thiophene, manufacturing method thereof, and pharmaceutical application of same | SLC10A6, TPMT, SLC6A6 | HPGD 2842/4885TP53 4012/4885KDM4E 1541/4885 |
| US-20200140423-A1 | Thiophene, Manufacturing Method Thereof, And Pharmaceutical Application Of Same | SLC10A6, TPMT, SLC6A6 | HPGD 2842/4885TP53 4012/4885KDM4E 1541/4885 |
| US-20050228018-A1 | Chemical compounds | CMA1, TPSB2, TPSG1 | HPGD 420/4885TP53 4261/4885KDM4E 3000/4885 |
| US-20030187020-A1 | Chemical compounds | CMA1, TPSB2, TPSG1 | HPGD 420/4885TP53 4261/4885KDM4E 3000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.