Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5241115 | 0.75 | MTNR1A (0.47) | GPR84MAOAMTNR1AMTNR1BPTGS2 | |
| SCHEMBL826206 | 0.74 | — | — | |
| SCHEMBL1578071 | 0.73 | MAOA (0.42) | GPR84MAOAMTNR1AMTNR1BPTGS2 | |
| SCHEMBL29714904 | 0.73 | MAOA (0.42) | GPR84MAOAMTNR1AMTNR1BPTGS2 | |
| SCHEMBL29714906 | 0.73 | MAOA (0.42) | GPR84MAOAMTNR1AMTNR1BPTGS2 | |
| SCHEMBL7174565 | 0.72 | PTGS2 (0.57) | GPR84MAOAMTNR1AMTNR1BPTGS2 | |
| SCHEMBL29672905 | 0.71 | PTGS2 (0.67) | GPR84MAOAMTNR1AMTNR1BPTGS2 | |
| SCHEMBL7180542 | 0.71 | PTGS2 (0.67) | GPR84MAOAMTNR1AMTNR1BPTGS2 | |
| Fluorene SCHEMBL31388525 | 0.71 | MAOA (0.68) | MAOAMAPTKDM4ENPC1ALDH1A1 | |
| Fluorene SCHEMBL8180 | 0.71 | MAOA (0.68) | MAOAMAPTKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039126-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2011-10-18 | — | — | US | disclosed |
| EP-1299405-B1 | POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-05-13 | — | — | EP | disclosed |
| US-20090058289-A1 | Materials for Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2009-03-05 | — | — | US | disclosed |
| US-20050107608-A1 | Ligands for use in catalytic processes | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH ETHZ (CH) | 2005-05-19 | — | — | US | disclosed |
| US-6800701-B2 | USING COORDINATION CATALYSTS | DOW GLOBAL TECHNOLOGIES INC. | 2004-10-05 | — | — | US | disclosed |
| US-20030216529-A1 | Polycyclic, fused ring compounds, metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2003-11-20 | — | — | US | disclosed |
| US-6613921-B2 | Ligand comprising at least: a cyclopentadienyl ring, a 6,7,or 8 membered ring other than a 6-carbon aromatic ring, and an aromatic ring; said 6, 7, or 8 membered ring, is fused to both the cyclopentadienyl and the aromatic ring | DOW GLOBAL TECHNOLOGIES INC. | 2003-09-02 | — | — | US | disclosed |
| US-20020062011-A1 | Polycyclic, fused ring compounds, metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2002-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216529-A1 | Polycyclic, fused ring compounds, metal complexes and polymerization process | PIN1, ZC3H18, ORC3 | GPR84 4581/4885MAOA 1784/4885MTNR1A 4175/4885 |
| US-20090058289-A1 | Materials for Organic Electroluminescent Devices | PNMT, TES, TERT | GPR84 2480/4885MAOA 21/4885MTNR1A 3132/4885 |
| US-20050107608-A1 | Ligands for use in catalytic processes | PNKP, ITPA, PLCG2 | GPR84 1949/4885MAOA 1611/4885MTNR1A 4216/4885 |
| US-20020062011-A1 | Polycyclic, fused ring compounds, metal complexes and polymerization process | PIN1, ZC3H18, ORC3 | GPR84 4581/4885MAOA 1784/4885MTNR1A 4175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.