Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.34 |
| ▸ | CTSL | P07711 | 8/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 4/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3995145 | 0.85 | CTSL (0.43) | CTSKCTSLITGB3ITGA2BCTSS | |
| SCHEMBL4657546 | 0.83 | ABCB1 (0.40) | CTSKCTSLCTSSABCB1CTSB | |
| SCHEMBL3989591 | 0.80 | MC4R (0.30) | — | |
| SCHEMBL13796817 | 0.80 | MC4R (0.30) | — | |
| SCHEMBL3989379 | 0.78 | ABCB1 (0.36) | CTSKCTSLCTSSABCB1CTSB | |
| SCHEMBL3988356 | 0.78 | — | — | |
| SCHEMBL3989537 | 0.75 | MMP1 (0.39) | CTSLCTSSCTSBALDH1A1 | |
| SCHEMBL4657429 | 0.68 | NPC1 (0.39) | ALDH1A1 | |
| SCHEMBL4657436 | 0.68 | NPC1 (0.39) | ALDH1A1 | |
| SCHEMBL4656090 | 0.66 | CTSS (0.45) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |