Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 11/20 | 0.43 |
| ▸ | CTSK | P43235 | 10/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 6/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989609 | 0.85 | CTSK (0.34) | CTSLCTSKCTSSITGB3ITGA2B | |
| SCHEMBL3988356 | 0.78 | — | — | |
| SCHEMBL3989464 | 0.77 | CTSL (0.45) | CTSLCTSKCTSS | |
| SCHEMBL3989460 | 0.77 | CTSL (0.45) | CTSLCTSKCTSS | |
| SCHEMBL3989467 | 0.76 | CTSB (0.50) | CTSLCTSKCTSS | |
| SCHEMBL13964643 | 0.75 | IDO1 (0.51) | CTSLCTSKIDO1TDO2CTSS | |
| SCHEMBL7082474 | 0.71 | CTSK (0.51) | CTSLCTSKIDO1TDO2CTSS | |
| SCHEMBL4657113 | 0.70 | SYK (0.60) | CTSLCTSKCTSS | |
| SCHEMBL3988336 | 0.70 | PTPRB (0.46) | CTSLCTSKCTSSITGB3ITGA2B | |
| SCHEMBL3989682 | 0.70 | TACR1 (0.48) | CTSLCTSSTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |