Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | IAPP | P10997 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD5 | P21918 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29655817 | 1.00 | KDM4E (0.50) | KDM4EMAPTHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL29764187 | 0.91 | ALOX15 (0.51) | KDM4EMAPTHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL22798842 | 0.86 | KDM4E (0.51) | KDM4EMAPTHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL22798841 | 0.86 | KDM4E (0.51) | KDM4EMAPTHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL339754 | 0.84 | XDH (0.49) | KDM4EMAPTHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL339752 | 0.84 | XDH (0.49) | KDM4EMAPTHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL1027806 | 0.77 | GRIK1 (0.50) | ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL22799190 | 0.75 | COPS5 (0.38) | KDM4EMAPTHSD17B10BLMHPGD | |
| SCHEMBL31230163 | 0.75 | COPS5 (0.38) | KDM4EMAPTHSD17B10BLMHPGD | |
| Dopamine SCHEMBL28657094 | 0.75 | KDM4E (0.78) | KDM4EMAPTHIF1AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114524951-B | Polydopamine drug delivery carrier and application thereof | 温州医科大学附属眼视光医院 | 2023-11-21 | — | — | CN | disclosed |
| CN-107532050-B | Pressure sensitive adhesive for transdermal drug delivery | 诺芬药品公司 | 2021-03-02 | — | — | CN | disclosed |
| US-10406116-B2 | Pressure-sensitive adhesives for transdermal drug delivery | NOVEN PHARMACEUTICALS, INC. (US) | 2019-09-10 | — | — | US | disclosed |
| US-10406115-B2 | Pressure-sensitive adhesives for transdermal drug delivery | NOVEN PHARMACEUTICALS, INC. (US) | 2019-09-10 | — | — | US | disclosed |
| EP-3506889-A1 | PRESSURE-SENSITIVE ADHESIVES FOR TRANSDERMAL DRUG DELIVERY | Noven Pharmaceuticals, INC. (US) | 2019-07-10 | — | — | EP | disclosed |
| US-10177383-B2 | Nano-coating material, method for manufacturing same, coating agent, functional material, and method for manufacturing same | NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) | 2019-01-08 | — | — | US | disclosed |
| WO-2018026759-A1 | PRESSURE-SENSITIVE ADHESIVES FOR TRANSDERMAL DRUG DELIVERY | NOVEN PHARMACEUTICALS, INC. (US) | 2018-02-08 | — | — | WO | disclosed |
| CN-107532050-A | Contact adhesive for cutaneous penetration | 诺芬药品公司 | 2018-01-02 | — | — | CN | disclosed |
| US-20170214047-A1 | NANO-COATING MATERIAL, METHOD FOR MANUFACTURING SAME, COATING AGENT, FUNCTIONAL MATERIAL, AND METHOD FOR MANUFACTURING SAME | NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) | 2017-07-27 | — | — | US | disclosed |
| US-20170129999-A1 | PH Responsive Self-Healing Hydrogels Formed By Boronate-Catechol Complexation | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2017-05-11 | — | — | US | disclosed |
| US-20120329882-A1 | pH Responsive Self-Heating Hydrogels Formed By Boronate-Catechol Complexation | NORTHWESTERN UNIVERSITY (US) | 2012-12-27 | — | — | US | disclosed |
| WO-2012159106-A2 | PH RESPONSIVE SELF-HEALING HYDROGELS FORMED BY BORONATE-CATECHOL COMPLEXATION | NORTHWESTERN UNIVERSITY (US) | 2012-11-22 | — | — | WO | disclosed |
| US-20120157602-A1 | COPOLYMERS HAVING ZWITTERIONIC MOIETIES AND DIHDROXYPHENYL MOIETIES AND MEDICAL DEVICES COATED WITH THE COPOLYMERS | ABBOTT LABORATORIES (US) | 2012-06-21 | — | — | US | disclosed |
| US-8202956-B2 | Copolymers having zwitterionic moieties and dihydroxyphenyl moieties and medical devices coated with the copolymers | ABBOTT LABORATORIES (US) | 2012-06-19 | — | — | US | disclosed |
| US-8101156-B2 | Methods of manufacturing copolymers with zwitterionic moieties and dihydroxyphenyl moieties and use of same | ABBOTT LABORATORIES (US) | 2012-01-24 | — | — | US | disclosed |
| US-20110166250-A1 | COPOLYMERS HAVING ZWITTERIONIC MOIETIES AND DIHYDROXYPHENYL MOIETIES AND MEDICAL DEVICES COATED WITH THE COPOLYMERS | ABBOTT LABORATORIES (US) | 2011-07-07 | — | — | US | disclosed |
| US-20110160382-A1 | COPOLYMERS HAVING ZWITTERIONIC MOIETIES AND DIHDROXYPHENYL MOIETIES AND MEDICAL DEVICES COATED WITH THE COPOLYMERS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | US | disclosed |
| US-7928176-B2 | Copolymers having zwitterionic moieties and dihydroxyphenyl moieties and medical devices coated with the copolymers | ABBOTT LABORATORIES (US) | 2011-04-19 | — | — | US | disclosed |
| US-20080153923-A1 | Biocompatible polymer; copolymerize a dihydroxyphenyl monomer with acrylate comonomer to yield intermediate polymer; coupling zwitterionic phosphorylcholine to the acrylate comonomer of intermediate product to yield a thermoplastic polymer; improved adhesion to surface of implantable medical device | ABBOTT LABORATORIES (US) | 2008-06-26 | — | — | US | disclosed |
| US-20080139746-A1 | Polymer preferably includes methacryloyloxyethyl phosphorylcholine, and a cationic monomer, a monomer with a pendant hydrocarbon group or a monomer with a pendant hydrophilic group; blends with polyvinylpyrrolidone, a polyacrylate or terpolymer; improved adhesion, primers not needed; stent coatings | ABBOTT LABORATORIES (US) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153923-A1 | Biocompatible polymer; copolymerize a dihydroxyphenyl monomer with acrylate comonomer to yield intermediate polymer; coupling zwitterionic phosphorylcholine to the acrylate comonomer of intermediate product to yield a thermoplastic polymer; improved adhesion to surface of implantable medical device | CAD, PHOSPHO1, CD14 | KDM4E 2706/4885MAPT 1613/4885HIF1A 2628/4885 |
| US-20170129999-A1 | PH Responsive Self-Healing Hydrogels Formed By Boronate-Catechol Complexation | DBH, BAP1, APEX1 | KDM4E 1114/4885MAPT 3929/4885HIF1A 400/4885 |
| US-20120329882-A1 | pH Responsive Self-Heating Hydrogels Formed By Boronate-Catechol Complexation | DBH, BAP1, HAO2 | KDM4E 1243/4885MAPT 3539/4885HIF1A 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.