Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.46 |
| ▸ | RECQL | P46063 | 6/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | FYN | P06241 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | BLM | P54132 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339754 | 1.00 | XDH (0.49) | XDHKDM4EHSD17B10ALOX15TDP1 | |
| SCHEMBL29655817 | 0.84 | KDM4E (0.50) | KDM4EHSD17B10ALOX15TDP1HIF1A | |
| SCHEMBL400289 | 0.84 | KDM4E (0.50) | KDM4EHSD17B10ALOX15TDP1HIF1A | |
| SCHEMBL3870569 | 0.83 | ALDH1A1 (0.41) | KDM4EHSD17B10ALOX15TDP1HIF1A | |
| SCHEMBL29764187 | 0.81 | ALOX15 (0.51) | KDM4EHSD17B10ALOX15TDP1HIF1A | |
| SCHEMBL3869765 | 0.81 | CA2 (0.47) | KDM4ESLC7A5ALDH1A1BLMTRPA1 | |
| SCHEMBL1291989 | 0.78 | XDH (0.59) | XDHKDM4EHSD17B10ALOX15TDP1 | |
| SCHEMBL1788431 | 0.77 | IDO1 (0.43) | ALDH1A1LMNATRPA1CYP1A2TAAR1 | |
| SCHEMBL554390 | 0.75 | ALDH1A1 (0.42) | TDP1PTGS1SLC7A5HPGDALDH1A1 | |
| SCHEMBL554389 | 0.75 | ALDH1A1 (0.42) | TDP1PTGS1SLC7A5HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367091-B2 | Coatings for implantable medical devices | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-8097268-B2 | Coatings for implantable medical devices | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2012-01-17 | — | — | US | disclosed |
| US-20090252780-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2009-10-08 | — | — | US | disclosed |
| US-20090248146-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2009-10-01 | — | — | US | disclosed |
| US-7563454-B1 | Coatings for implantable medical devices | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2009-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090252780-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES | AOC1, TFRC, CD59 | XDH 1739/4885KDM4E 1741/4885HSD17B10 4681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.