Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | HEXA | P06865 | 1/20 | 0.40 |
| ▸ | HEXB | P07686 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039244 | 0.87 | HSD17B10 (0.42) | RAB9AMAPK14HEXAHEXBKCNT1 | |
| SCHEMBL4010057 | 0.85 | DPP4 (0.48) | LDHALDHBFABP3FABP4FABP5 | |
| SCHEMBL4011136 | 0.82 | RAB9A (0.38) | RAB9ARORCMAPK14KMOPIN1 | |
| SCHEMBL4008747 | 0.79 | KCNT1 (0.38) | RAB9ARORCMAPK14HEXAHEXB | |
| SCHEMBL4011470 | 0.79 | FABP3 (0.45) | FABP3FABP4FABP5RAB9ANPSR1 | |
| SCHEMBL5509874 | 0.72 | KDM4E (0.55) | FABP3FABP4FABP5RAB9APDE4B | |
| SCHEMBL8038540 | 0.72 | GCGR (0.45) | RAB9AHTTDPP4DPP8DPP9 | |
| SCHEMBL11312445 | 0.68 | KDM4E (0.57) | FABP3FABP4FABP5RAB9AHEXA | |
| SCHEMBL4005140 | 0.68 | FABP3 (0.44) | FABP3FABP4FABP5RAB9AHEXA | |
| SCHEMBL4010066 | 0.68 | FABP3 (0.42) | FABP3FABP4FABP5RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |