Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.38 |
| ▸ | DHPS | P49366 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HEXA | P06865 | 1/20 | 0.37 |
| ▸ | HEXB | P07686 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011136 | 0.90 | RAB9A (0.38) | KCNT1RAB9ATSHRGAALMNA | |
| SCHEMBL4011273 | 0.86 | ADORA3 (0.38) | DHPSRAB9ATSHRMAPTTP53 | |
| SCHEMBL8039244 | 0.83 | HSD17B10 (0.42) | KCNT1RAB9ATSHRGAALMNA | |
| SCHEMBL4011133 | 0.79 | LDHA (0.41) | KCNT1RAB9ATSHRLMNAHEXA | |
| SCHEMBL4010063 | 0.70 | CNR1 (0.41) | RAB9ATSHRGAALMNAMAPT | |
| SCHEMBL4011472 | 0.70 | MAPT (0.39) | RAB9ATSHRLMNAPOLBMAPT | |
| SCHEMBL8038540 | 0.68 | GCGR (0.45) | RAB9ATSHRLMNAPOLBMAPT | |
| SCHEMBL9363654 | 0.65 | MAPT (0.49) | RAB9AGAALMNAMAPTALDH1A1 | |
| SCHEMBL4010057 | 0.64 | DPP4 (0.48) | RAB9AGAALMNAPOLBMAPT | |
| SCHEMBL3766697 | 0.63 | RAB9A (0.73) | RAB9ATSHRPOLBTP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |