Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HEXA | P06865 | 1/20 | 0.38 |
| ▸ | HEXB | P07686 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | DHFR | P00374 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011133 | 0.87 | LDHA (0.41) | KMT2AKCNT1RAB9AMAPK14LMNA | |
| SCHEMBL8038540 | 0.86 | GCGR (0.45) | HSD17B10GCGRKMT2AALDH1A1RAB9A | |
| SCHEMBL4008747 | 0.83 | KCNT1 (0.38) | KMT2AKCNT1ALDH1A1RAB9AMAPK14 | |
| SCHEMBL8024870 | 0.80 | GCGR (0.44) | GCGRKMT2AALDH1A1RAB9ALMNA | |
| SCHEMBL4011136 | 0.80 | RAB9A (0.38) | KMT2AKCNT1RAB9AMAPK14GAA | |
| SCHEMBL5521948 | 0.73 | KDM4E (0.56) | HSD17B10KMT2AALDH1A1RAB9AGAA | |
| SCHEMBL4010057 | 0.72 | DPP4 (0.48) | GCGRALDH1A1RAB9AGAALMNA | |
| SCHEMBL8038524 | 0.70 | GCGR (0.43) | GCGRKMT2AALDH1A1RAB9ALMNA | |
| SCHEMBL8031430 | 0.70 | CNR2 (0.41) | KMT2AALDH1A1RAB9ALMNATSHR | |
| SCHEMBL8027046 | 0.70 | ADORA3 (0.41) | HSD17B10KMT2AALDH1A1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |