Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 4/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | PRKACG | P22612 | 1/20 | 0.33 |
| ▸ | PRKACB | P22694 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1813625 | 1.00 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3BIRC5MGLL | |
| SCHEMBL4169878 | 0.87 | MGLL (0.42) | MGLLHTR6MAPT | |
| SCHEMBL4167473 | 0.87 | MGLL (0.35) | SLC6A4SLC6A2SLC6A3MGLL | |
| SCHEMBL4158782 | 0.85 | FFAR4 (0.39) | SLC6A4SLC6A2SLC6A3MGLLHRH3 | |
| SCHEMBL4162409 | 0.85 | FFAR4 (0.33) | SLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL4164731 | 0.85 | FFAR4 (0.33) | SLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL4164927 | 0.85 | P2RX7 (0.33) | HTR6MAPT | |
| SCHEMBL4166486 | 0.84 | KDM2B (0.40) | MAPT | |
| SCHEMBL2884746 | 0.83 | HRH3 (0.51) | MGLLHTR6HRH3 | |
| SCHEMBL1814722 | 0.82 | KHK (0.44) | SLC6A4SLC6A2SLC6A3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074088-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008045371-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-04-17 | — | — | WO | disclosed |