Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | PCSK9 | Q8NBP7 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | RPLP1 | P05386 | 2/20 | 0.31 |
| ▸ | RPLP0 | P05388 | 2/20 | 0.31 |
| ▸ | RPS17 | P08708 | 2/20 | 0.31 |
| ▸ | RPSA | P08865 | 2/20 | 0.31 |
| ▸ | RPS2 | P15880 | 2/20 | 0.31 |
| ▸ | RPL35A | P18077 | 2/20 | 0.31 |
| ▸ | RPL7 | P18124 | 2/20 | 0.31 |
| ▸ | RPL17 | P18621 | 2/20 | 0.31 |
| ▸ | RPS4Y1 | P22090 | 2/20 | 0.31 |
| ▸ | RPS3 | P23396 | 2/20 | 0.31 |
| ▸ | RPS12 | P25398 | 2/20 | 0.31 |
| ▸ | RPL13 | P26373 | 2/20 | 0.31 |
| ▸ | RPL10 | P27635 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4162409 | 0.89 | FFAR4 (0.33) | FFAR4MAPTKMT2AMEN1SLC6A2 | |
| SCHEMBL4164731 | 0.89 | FFAR4 (0.33) | FFAR4MAPTKMT2AMEN1SLC6A2 | |
| SCHEMBL1813625 | 0.85 | SLC6A4 (0.37) | HRH3MAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4013186 | 0.85 | SLC6A4 (0.37) | HRH3MAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4791706 | 0.84 | HRH3 (0.35) | HRH3KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4164927 | 0.78 | P2RX7 (0.33) | MAPTKMT2AMEN1RECQL | |
| SCHEMBL4167473 | 0.78 | MGLL (0.35) | SLC6A2SLC6A4SLC6A3MGLL | |
| SCHEMBL4169878 | 0.78 | MGLL (0.42) | KCNH2MAPTKMT2AMEN1MGLL | |
| SCHEMBL4166486 | 0.76 | KDM2B (0.40) | MAPTALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL1814722 | 0.76 | KHK (0.44) | SLC6A2SLC6A4SLC6A3GAAMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074088-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth (US) | 2009-07-01 | — | — | EP | claimed |
| WO-2008045371-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-04-17 | — | — | WO | claimed |