Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 17/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4169878 | 0.86 | MGLL (0.42) | TFPI2MEN1MAPTKMT2A | |
| SCHEMBL4167473 | 0.86 | MGLL (0.35) | KDM2B | |
| SCHEMBL4013186 | 0.84 | SLC6A4 (0.37) | MAPT | |
| SCHEMBL1813625 | 0.84 | SLC6A4 (0.37) | MAPT | |
| SCHEMBL3844268 | 0.81 | POLB (0.42) | KDM2BKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL5128971 | 0.80 | MTNR1A (0.42) | KDM2BALDH1A1 | |
| SCHEMBL4162409 | 0.76 | FFAR4 (0.33) | MEN1MAPTKMT2A | |
| SCHEMBL4158782 | 0.76 | FFAR4 (0.39) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL4164731 | 0.76 | FFAR4 (0.33) | MEN1MAPTKMT2A | |
| SCHEMBL4164927 | 0.76 | P2RX7 (0.33) | MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074088-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth (US) | 2009-07-01 | — | — | EP | claimed |
| WO-2008045371-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-04-17 | — | — | WO | claimed |