Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4162409 | 1.00 | FFAR4 (0.33) | FFAR4SSTR4MEN1MAPTRECQL | |
| SCHEMBL4158782 | 0.89 | FFAR4 (0.39) | FFAR4MEN1MAPTRECQLKMT2A | |
| SCHEMBL4164927 | 0.85 | P2RX7 (0.33) | SSTR4MEN1MAPTRECQLKMT2A | |
| SCHEMBL1813625 | 0.85 | SLC6A4 (0.37) | MAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4013186 | 0.85 | SLC6A4 (0.37) | MAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4169878 | 0.81 | MGLL (0.42) | MEN1MAPTRECQLKMT2A | |
| SCHEMBL4167473 | 0.78 | MGLL (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4166486 | 0.76 | KDM2B (0.40) | MEN1MAPTKMT2A | |
| SCHEMBL1814722 | 0.76 | KHK (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4791706 | 0.75 | HRH3 (0.35) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074088-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008045371-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-04-17 | — | — | WO | disclosed |