Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167473 | 0.89 | MGLL (0.35) | MGLLFAAHHPGD | |
| SCHEMBL4013186 | 0.87 | SLC6A4 (0.37) | MGLLHTR6MAPT | |
| SCHEMBL1813625 | 0.87 | SLC6A4 (0.37) | MGLLHTR6MAPT | |
| SCHEMBL4166486 | 0.86 | KDM2B (0.40) | TFPI2MEN1MAPTKMT2A | |
| SCHEMBL4158337 | 0.84 | SMO (0.44) | MGLLHPGDS | |
| SCHEMBL4162409 | 0.81 | FFAR4 (0.33) | MEN1MAPTRECQLKMT2A | |
| SCHEMBL4164731 | 0.81 | FFAR4 (0.33) | MEN1MAPTRECQLKMT2A | |
| SCHEMBL4164927 | 0.81 | P2RX7 (0.33) | HTR6MEN1MAPTRECQLKMT2A | |
| SCHEMBL4012517 | 0.80 | GCG (0.35) | KCNH2MEN1MAPTRECQLKMT2A | |
| SCHEMBL4158782 | 0.78 | FFAR4 (0.39) | MGLLKCNH2MEN1MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074088-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth (US) | 2009-07-01 | — | — | EP | claimed |
| WO-2008045371-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-04-17 | — | — | WO | claimed |