Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | LYN | P07948 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4164731 | 0.85 | FFAR4 (0.33) | MEN1MAPTRECQLKMT2ASSTR4 | |
| SCHEMBL4162409 | 0.85 | FFAR4 (0.33) | MEN1MAPTRECQLKMT2ASSTR4 | |
| SCHEMBL1813625 | 0.85 | SLC6A4 (0.37) | HTR6MAPT | |
| SCHEMBL4013186 | 0.85 | SLC6A4 (0.37) | HTR6MAPT | |
| SCHEMBL4169878 | 0.81 | MGLL (0.42) | HTR6MEN1MAPTRECQLKMT2A | |
| SCHEMBL4158782 | 0.78 | FFAR4 (0.39) | MEN1MAPTRECQLKMT2A | |
| SCHEMBL4167473 | 0.78 | MGLL (0.35) | — | |
| SCHEMBL4166486 | 0.76 | KDM2B (0.40) | MEN1MAPTKMT2A | |
| SCHEMBL1814722 | 0.74 | KHK (0.44) | — | |
| SCHEMBL3846301 | 0.73 | SCN9A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074088-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth (US) | 2009-07-01 | — | — | EP | claimed |
| WO-2008045371-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-04-17 | — | — | WO | claimed |