Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GMNN | O75496 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974601 | 0.95 | TSHR (0.42) | TSHRBLMHSD17B10GMNNUSP2 | |
| SCHEMBL16673362 | 0.95 | TSHR (0.42) | TSHRBLMHSD17B10GMNNUSP2 | |
| SCHEMBL11460242 | 0.91 | TSHR (0.37) | TSHRBLMHSD17B10GMNNUSP2 | |
| SCHEMBL6890254 | 0.91 | TSHR (0.37) | TSHRBLMHSD17B10GMNNUSP2 | |
| SCHEMBL5066707 | 0.91 | TSHR (0.42) | TSHRBLMHSD17B10GMNNUSP2 | |
| SCHEMBL4657333 | 0.91 | TSHR (0.42) | TSHRBLMHSD17B10GMNNUSP2 | |
| SCHEMBL11523097 | 0.90 | TSHR (0.38) | TSHRLMNAF7F3 | |
| SCHEMBL8350454 | 0.88 | TSHR (0.39) | TSHRBLMHSD17B10GMNNUSP2 | |
| SCHEMBL5911729 | 0.88 | TSHR (0.36) | TSHRFAAHTRPV1F7F3 | |
| SCHEMBL17868374 | 0.86 | FAAH (0.54) | BLMHSD17B10GMNNUSP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247608-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-12-10 | — | — | WO | disclosed |
| US-10221169-B2 | Substituted aminothiazoles for the treatment of tuberculosis | THE BROAD INSTITUTE, INC. (US) | 2019-03-05 | — | — | US | disclosed |
| US-20170305895-A1 | SUBSTITUTED AMINOTHIAZOLES FOR THE TREATMENT OF TUBERCULOSIS | THE GENERAL HOSPITAL CORPORATION | 2017-10-26 | — | — | US | disclosed |
| EP-2074089-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2009-07-01 | — | — | EP | disclosed |
| US-7470693-B2 | Oxalamide derivatives as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-30 | — | — | US | disclosed |
| WO-2008048991-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2008-04-24 | — | — | WO | disclosed |
| US-20060241104-A1 | Oxalamide derivatives as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241104-A1 | Oxalamide derivatives as kinase inhibitors | PDK1, OAT, PDXK | TSHR 3492/4885BLM 2863/4885HSD17B10 1042/4885 |
| US-20170305895-A1 | SUBSTITUTED AMINOTHIAZOLES FOR THE TREATMENT OF TUBERCULOSIS | AADAT, ABAT, AASDHPPT | TSHR 825/4885BLM 4212/4885HSD17B10 1296/4885 |
| US-10221169-B2 | Substituted aminothiazoles for the treatment of tuberculosis | AADAT, ABAT, AASDHPPT | TSHR 825/4885BLM 4212/4885HSD17B10 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.