Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025980 | 0.87 | ERCC1 (0.48) | MEN1KMT2APGAM1ALDH1A1RAD52 | |
| SCHEMBL4026962 | 0.81 | F2 (0.39) | ALDH1A1 | |
| SCHEMBL4028019 | 0.78 | FEN1 (0.39) | — | |
| SCHEMBL4028505 | 0.76 | ALDH1A1 (0.38) | ALDH1A1CA2CA9MAPTGAA | |
| SCHEMBL4031044 | 0.74 | NTRK1 (0.41) | ALDH1A1POLBMAPTLMNA | |
| SCHEMBL4027166 | 0.74 | MEN1 (0.37) | MEN1KMT2AALDH1A1CA2CA9 | |
| SCHEMBL4034538 | 0.74 | ERCC1 (0.35) | MEN1KMT2AMAPTLMNA | |
| SCHEMBL4031769 | 0.74 | FEN1 (0.38) | ALDH1A1POLBMAPTLMNASMN1; SMN2 | |
| SCHEMBL4027681 | 0.73 | ERCC1 (0.41) | KMT2AALDH1A1POLBMAPTTDP1 | |
| SCHEMBL4029257 | 0.73 | FEN1 (0.44) | MEN1KMT2AALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470113-B1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-01-07 | — | — | EP | claimed |