SCHEMBL403336

SCHEMBL403336

C[Si](C)(C)O[Si](C)(C)O[Si](C)(CCCOCCO)O[Si](C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
THRB P10828 1/20 0.37
HTT P42858 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10301169 0.98 MEN1 (0.40) TSHRMEN1KMT2ATHRBHTT
SCHEMBL14867188 0.98 MEN1 (0.40) TSHRMEN1KMT2ATHRBHTT
SCHEMBL26921062 0.98 TSHR (0.39) TSHRMEN1KMT2ATHRBHTT
SCHEMBL10029816 0.98 TSHR (0.39) TSHRMEN1KMT2ATHRBHTT
SCHEMBL14867187 0.98 MEN1 (0.40) TSHRMEN1KMT2ATHRBHTT
SCHEMBL10301180 0.97 MEN1 (0.39) TSHRMEN1KMT2ATHRBHTT
SCHEMBL19822569 0.95 TSHR (0.37) TSHRMEN1KMT2ATHRBHTT
SCHEMBL17617967 0.95 MEN1 (0.40) TSHRMEN1KMT2ATHRBHTT
SCHEMBL12266699 0.93 TSHR (0.46) TSHRMEN1KMT2ATHRBHTT
SCHEMBL25495227 0.92 TSHR (0.37) TSHRMEN1KMT2ATHRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4240148-B1 METHOD FOR LOW VOLUME SPRAY APPLICATION BAYER AG (DE) 2025-11-12 EP disclosed
US-20230295433-A1 SILICONE EMULSION COMPOSITION AND FIBER TREATMENT AGENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-21 US disclosed
US-11744789-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, a colored effect pigment and a sealing reagent III HENKEL AG & CO. KGAA (US) 2023-09-05 US disclosed
US-11654095-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, a chromophoric compound, a modified fatty acid ester and a sealing reagent II HENKEL AG & CO. KGAA (DE) 2023-05-23 US disclosed
US-11655341-B2 Method for preparing a radical-polymerizable organopolysiloxane, a radiation-curable organopolysiloxane composition, and a release sheet SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-23 US disclosed
EP-3994993-A1 LOW DRIFT, RAINFASTNESS, HIGH SPREADING AND ULV TANK MIX ADJUVANT FORMULATION Bayer Aktiengesellschaft (DE) 2022-05-11 EP disclosed
EP-3994981-A1 METHOD FOR LOW VOLUME SPRAY APPLICATION Bayer Aktiengesellschaft (DE) 2022-05-11 EP disclosed
EP-3994995-A1 LOW DRIFT, RAINFASTNESS, HIGH SPREADING, HIGH UPTAKE AND ULV TANK MIX ADJUVANT FORMULATION Bayer Aktiengesellschaft (DE) 2022-05-11 EP disclosed
EP-3994986-A1 AGROCHEMICAL COMPOSITION WITH IMPROVED DRIFT AND SPREADING PROPERTIES Bayer Aktiengesellschaft (DE) 2022-05-11 EP disclosed
EP-3994994-A1 LOW DRIFT, RAINFASTNESS, HIGH SPREADING, HIGH UPTAKE AND ULV TANK MIX ADJUVANT FORMULATION Bayer Aktiengesellschaft (DE) 2022-05-11 EP disclosed
US-20170216156-A1 PERFORMANCE-ENHANCED ANTIPERSPIRANTS HENKEL AG & CO. KGAA (DE) 2017-08-03 US disclosed
US-9371458-B2 Ink composition for ink jet recording and ink jet recording method SEIKO EPSON CORPORATION (JP) 2016-06-21 US disclosed
US-8697101-B2 Polysiloxane antimicrobials BASF SE (DE) 2014-04-15 US disclosed
US-20120061877-A1 Hyrdophilic Surface Modification of Polydimethylsiloxane UTAH STATE UNIVERSITY (US) 2012-03-15 US disclosed
US-20120052374-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS ELECTROLYTE BATTERY SONY CORPORATION (JP) 2012-03-01 US disclosed
US-20110251417-A1 Partially Hydrocarbon Group-Blocked (Poly)Glycerol-Modified Polysiloxane, Method For Producing The Same, And Cosmetic Composition Containing The Same DOW TORAY CO., LTD. (JP) 2011-10-13 US disclosed
US-8034891-B2 Polyether-modified organopolysiloxane, diorganopolysiloxane-polyether block copolymer, their production methods, and cosmetic preparation DOW CORNING TORAY COMPANY, LTD. (JP) 2011-10-11 US disclosed
US-20110110998-A1 POLYSILOXANE ANTIMICROBIALS BASF SE (DE) 2011-05-12 US disclosed
US-20100036062-A1 Polyether-Modified Organopolysiloxane, Diorganopolysiloxane-Polyether Block Copolymer, Their Production Methods, and Cosmetic Preparation DOW TORAY CO., LTD. (JP) 2010-02-11 US disclosed
US-20070026509-A1 Novel surface-active polysiloxane photoinitiators CIBA SPECIALTY CHEMICALS CORP. 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110251417-A1 Partially Hydrocarbon Group-Blocked (Poly)Glycerol-Modified Polysiloxane, Method For Producing The Same, And Cosmetic Composition Containing The Same PFAS, NOTUM, FGB TSHR 4479/4885MEN1 4360/4885KMT2A 519/4885
US-11654095-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, a chromophoric compound, a modified fatty acid ester and a sealing reagent II FABP2, KRT18, FABP4 TSHR 4852/4885MEN1 2991/4885KMT2A 654/4885
US-11744789-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, a colored effect pigment and a sealing reagent III KRT18, JUP, EPCAM TSHR 4698/4885MEN1 673/4885KMT2A 2385/4885
US-11655341-B2 Method for preparing a radical-polymerizable organopolysiloxane, a radiation-curable organopolysiloxane composition, and a release sheet MUS81, MSR1, H1-4 TSHR 147/4885MEN1 490/4885KMT2A 1452/4885
US-20110110998-A1 POLYSILOXANE ANTIMICROBIALS SIGMAR1, MSR1, TLR5 TSHR 296/4885MEN1 4731/4885KMT2A 4067/4885
US-20170216156-A1 PERFORMANCE-ENHANCED ANTIPERSPIRANTS ALOX5, ALKBH3, ALOX15 TSHR 2758/4885MEN1 4525/4885KMT2A 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.