Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | EGLN1 | Q9GZT9 | 11/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11770828 | 0.87 | EGLN1 (0.49) | L3MBTL1EGLN1ALDH1A1NPC1RAB9A | |
| SCHEMBL14414488 | 0.82 | EGLN1 (0.51) | L3MBTL1EGLN1ALDH1A1HSP90AA1KDM4E | |
| SCHEMBL9310765 | 0.80 | ALDH1A1 (0.56) | L3MBTL1EGLN1ALDH1A1NPC1RAB9A | |
| SCHEMBL12722433 | 0.79 | CTSB (0.53) | L3MBTL1EGLN1ALDH1A1HSP90AA1KDM4E | |
| SCHEMBL11955296 | 0.77 | BCHE (0.48) | L3MBTL1EGLN1ALDH1A1NPC1RAB9A | |
| SCHEMBL14775942 | 0.76 | EGLN1 (0.51) | L3MBTL1EGLN1ALDH1A1NPC1RAB9A | |
| SCHEMBL19323057 | 0.75 | L3MBTL1 (0.55) | L3MBTL1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL8342736 | 0.75 | MMP2 (0.55) | L3MBTL1EGLN1ALDH1A1NPC1RAB9A | |
| SCHEMBL1714944 | 0.74 | BCHE (0.49) | L3MBTL1EGLN1ALDH1A1NPC1RAB9A | |
| SCHEMBL11967425 | 0.74 | TERT (0.52) | L3MBTL1EGLN1ALDH1A1HSP90AA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611009-A | Quinoline derivatives | CHRONOGEN INC (US) | 2009-12-23 | — | — | CN | claimed |
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | claimed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | claimed |
| CN-101611009-A | Quinoline derivatives | CHRONOGEN INC (US) | 2009-12-23 | — | — | CN | disclosed |
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | disclosed |