Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041414 | 0.86 | KMT2A (0.46) | KMT2ANPSR1HPGDMAPTALDH1A1 | |
| SCHEMBL4032834 | 0.86 | ALDH1A1 (0.39) | KMT2ANPSR1HPGDMAPTALDH1A1 | |
| SCHEMBL4039393 | 0.85 | ATAD2 (0.42) | KMT2ANPSR1MAPTALDH1A1GAA | |
| SCHEMBL3915970 | 0.84 | KMT2A (0.45) | KMT2ANPSR1MAPTALDH1A1TSHR | |
| SCHEMBL4036735 | 0.79 | MAPT (0.43) | MAPTALDH1A1TSHRGAACYP2C19 | |
| SCHEMBL4037038 | 0.77 | SMN1; SMN2 (0.41) | KMT2ANPSR1MAPTPKMGAA | |
| SCHEMBL3918968 | 0.77 | GAA (0.46) | KMT2ANPSR1MAPTALDH1A1TSHR | |
| SCHEMBL1800410 | 0.77 | OPRM1 (0.32) | MAPTALDH1A1HDAC8 | |
| SCHEMBL2942272 | 0.76 | GAA (0.40) | ALDH1A1GAACYP2C19SMN1; SMN2 | |
| SCHEMBL4037470 | 0.76 | GAA (0.44) | KMT2ANPSR1MAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730144-B1 | SUBSTITUTED 1,4,8-TRIAZASPIRO¬4.5 DECAN-2-ONE COMPOUNDS | GRUENENTHAL GMBH (DE) | 2009-06-10 | — | — | EP | claimed |