Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047432 | 0.95 | ALDH1A1 (0.35) | CTSKPREPFAP | |
| SCHEMBL4051191 | 0.90 | CTSK (0.37) | CTSK | |
| SCHEMBL6241646 | 0.89 | CTSK (0.37) | CTSKPREPFAP | |
| SCHEMBL4052303 | 0.89 | CTSK (0.35) | CTSKPREPFAPP2RY12 | |
| SCHEMBL4045685 | 0.88 | PREP (0.34) | CTSKPREPFAP | |
| SCHEMBL4049326 | 0.88 | CTSK (0.42) | CTSKPREPFAPP2RY12 | |
| SCHEMBL4044808 | 0.88 | CTSK (0.36) | CTSKPREPFAP | |
| SCHEMBL4043203 | 0.88 | CTSK (0.35) | CTSKPREPFAPP2RY12 | |
| SCHEMBL4044090 | 0.88 | CTSK (0.34) | CTSKPREPFAP | |
| SCHEMBL4045577 | 0.87 | CTSK (0.41) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |