Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.31 |
| ▸ | PREP | P48147 | 2/20 | 0.31 |
| ▸ | FAP | Q12884 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046884 | 0.94 | CTSK (0.34) | CTSKELANECTSSPREPFAP | |
| SCHEMBL4045331 | 0.93 | CTSK (0.43) | CTSKELANECTSSPREPFAP | |
| SCHEMBL4039018 | 0.90 | HSD17B10 (0.36) | CTSKCTSSPREPFAPCHRNB2 | |
| SCHEMBL4043596 | 0.89 | ELANE (0.38) | CTSKELANEGPR132PREPFAP | |
| SCHEMBL4042570 | 0.88 | CTSK (0.34) | CTSKELANEPREPFAP | |
| SCHEMBL4043393 | 0.88 | FKBP1A (0.35) | CTSKCTSSCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL4039641 | 0.88 | CTSK (0.34) | CTSKPREPFAP | |
| SCHEMBL4050322 | 0.88 | CTSK (0.34) | CTSKELANEPREPFAP | |
| SCHEMBL4042672 | 0.86 | CTSK (0.41) | CTSKELANECTSSPREPFAP | |
| SCHEMBL4042885 | 0.86 | TGM2 (0.44) | CTSKCTSSTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |