Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.36 |
| ▸ | CTSL | P07711 | 9/20 | 0.33 |
| ▸ | CTSS | P25774 | 6/20 | 0.33 |
| ▸ | CTSB | P07858 | 5/20 | 0.33 |
| ▸ | CTSV | O60911 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045162 | 0.93 | TAS1R3 (0.34) | CTSKTAS1R3TAS1R1 | |
| SCHEMBL4043929 | 0.93 | CTSV (0.32) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL4041781 | 0.92 | CTSK (0.39) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL4043593 | 0.90 | USP2 (0.33) | CTSKTAS1R3TAS1R1 | |
| SCHEMBL4042354 | 0.90 | TAS1R3 (0.37) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL4046540 | 0.88 | CTSK (0.37) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4041991 | 0.86 | CTSK (0.46) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4047816 | 0.85 | CTSK (0.33) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4047148 | 0.84 | CHRNB2 (0.39) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL4044439 | 0.84 | CTSK (0.41) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |