Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | BMP1 | P13497 | 2/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044402 | 0.91 | GAA (0.36) | USP2GAATRPM8USP30BMP1 | |
| SCHEMBL4042300 | 0.90 | CTSK (0.37) | TAS1R3TAS1R1CTSK | |
| SCHEMBL4043929 | 0.90 | CTSV (0.32) | TAS1R3TAS1R1CTSK | |
| SCHEMBL4045162 | 0.90 | TAS1R3 (0.34) | TAS1R3TAS1R1CTSK | |
| SCHEMBL4049501 | 0.87 | CTSK (0.40) | TRPM8CTSK | |
| SCHEMBL4043432 | 0.85 | KCNQ1 (0.38) | USP2GAATRPM8USP30 | |
| SCHEMBL4038978 | 0.84 | USP30 (0.34) | TRPM8USP30BMP1CTSK | |
| SCHEMBL4051635 | 0.84 | HPGD (0.37) | GAATRPM8USP30BMP1CTSK | |
| SCHEMBL4045350 | 0.83 | CHRNB2 (0.34) | TRPM8USP30CTSK | |
| SCHEMBL4046322 | 0.83 | CHRNB2 (0.38) | TRPM8USP30TAS1R3TAS1R1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |