Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | MC1R | Q01726 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 3/20 | 0.32 |
| ▸ | FAP | Q12884 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041363 | 0.93 | CTSK (0.42) | CTSKMMP1MMP3MMP9PREP | |
| SCHEMBL4042699 | 0.91 | CTSK (0.32) | CTSKPREPFAP | |
| SCHEMBL4051650 | 0.90 | HSD17B10 (0.36) | CTSKPREPFAPMEN1KMT2A | |
| SCHEMBL4051965 | 0.89 | MC4R (0.38) | CTSKMC4RMC3RMC1RMMP1 | |
| SCHEMBL4044808 | 0.88 | CTSK (0.36) | CTSKPREPFAPELANE | |
| SCHEMBL4040719 | 0.88 | SMYD3 (0.35) | CTSKPREPFAPALDH1A1L3MBTL1 | |
| SCHEMBL4043203 | 0.88 | CTSK (0.35) | CTSKMC4RMC3RMC1RPREP | |
| SCHEMBL4050322 | 0.88 | CTSK (0.34) | CTSKPREPFAPELANEKMT2A | |
| SCHEMBL4046884 | 0.87 | CTSK (0.34) | CTSKMMP1MMP3PREPFAP | |
| SCHEMBL4046940 | 0.87 | KDM4E (0.35) | CTSKMC4RMC3RMC1RMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |