Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 4/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047237 | 0.93 | SMYD3 (0.35) | CTSKSMYD3CTSLCTSSALDH1A1 | |
| SCHEMBL4045208 | 0.93 | SMYD3 (0.35) | SMYD3ALDH1A1FKBP1A | |
| SCHEMBL4045926 | 0.90 | GPR132 (0.36) | CTSLCTSSFKBP1A | |
| SCHEMBL4043490 | 0.90 | CTSK (0.40) | CTSKSMYD3CTSLCTSSCTSB | |
| SCHEMBL4043196 | 0.89 | CTSK (0.39) | CTSKSMYD3CTSLCTSSCTSB | |
| SCHEMBL4043952 | 0.89 | CTSK (0.42) | CTSKCTSLCTSSCTSBFKBP1A | |
| SCHEMBL4048306 | 0.88 | CTSK (0.38) | CTSKSMYD3CTSLCTSSCTSB | |
| SCHEMBL4047118 | 0.88 | CTSK (0.41) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4050147 | 0.88 | CTSK (0.40) | CTSKSMYD3CTSLCTSSCTSB | |
| SCHEMBL4043147 | 0.87 | CTSK (0.40) | CTSKCTSLCTSSCTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |