SCHEMBL4043495

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4043502	0.89	TNKS (0.39)	PARP1PARP2TNKSPARP4PARP3
	SCHEMBL4046437	0.83	FKBP1A (0.41)	VNN1
	SCHEMBL6210597	0.81	PARP1 (0.40)	PARP1PARP2TNKSPARP4PARP3
	SCHEMBL4042835	0.79	HPGD (0.42)	NAMPTALDH1A1KDM4E
	SCHEMBL4037636	0.78	CTSK (0.42)	NAMPTFNTAFNTBMEN1KMT2A
	SCHEMBL4047936	0.78	C3AR1 (0.39)	PARP1PARP2TNKSPARP4PARP3
	SCHEMBL4039942	0.78	PARP1 (0.38)	PARP1PARP2TNKSPARP4PARP3
	SCHEMBL6208825	0.78	PAX8 (0.40)	PARP1PARP2TNKSPARP4PARP3
	SCHEMBL6210592	0.78	PAX8 (0.40)	PARP1PARP2TNKSPARP4PARP3
	SCHEMBL4037440	0.77	GPR132 (0.43)	NAMPTSIGMAR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.